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Annual Review of Biochemistry|March 31, 2023
The Inseparable Relationship Between Cholesterol and Hedgehog SignalingChristian Siebold, Rajat RohatgiNature Chemical Biology|November 17, 2020
Cholesterol access in cellular membranes controls Hedgehog signalingArun Radhakrishnan, Rajat Rohatgi, Christian SieboldDevelopment (Cambridge, England)|May 17, 2019
Biochemical mechanisms of vertebrate hedgehog signalingJennifer H Kong, Christian Siebold, Rajat RohatgiCurrent Opinion in Cell Biology|December 22, 2017
Multiple ligand binding sites regulate the Hedgehog signal transducer Smoothened in vertebratesEamon Fx Byrne, Giovanni Luchetti, Rajat Rohatgi, et al.Current Opinion in Structural Biology|June 28, 2019
Structures of vertebrate Patched and Smoothened reveal intimate links between cholesterol and Hedgehog signallingChristiane Kowatsch, Rachel E Woolley, Maia Kinnebrew, et al.Structure (London, England : 1993)|January 1, 2019
Cholesterol Interaction Sites on the Transmembrane Domain of the Hedgehog Signal Transducer and Class F G Protein-Coupled Receptor SmoothenedGeorge Hedger, Heidi Koldsø, Matthieu Chavent, et al.Biorxiv : the Preprint Server for Biology|February 24, 2023
The Energetics and Ion Coupling of Cholesterol Transport Through Patched1T Bertie Ansell, Robin A Corey, Lucrezia Vittoria Viti, et al.Science Advances|August 23, 2023
The energetics and ion coupling of cholesterol transport through Patched1T Bertie Ansell, Robin A Corey, Lucrezia Vittoria Viti, et al.Elife|October 6, 2016
Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signalingGiovanni Luchetti, Ria Sircar, Jennifer H Kong, et al.Methods in Molecular Biology (Clifton, N.J.)|July 17, 2015
Rapid Screening of Gli2/3 Mutants Using the Flp-In SystemPawel Niewiadomski, Rajat RohatgiPageof 16