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Journal of Natural Products|September 6, 2014
Semisynthetic analogues of toxiferine I and their pharmacological properties at α7 nAChRs, muscle-type nAChRs, and the allosteric binding site of muscarinic M2 receptorsDarius P Zlotos, Christian Tränkle, Ulrike Holzgrabe, et al.Journal of Medicinal Chemistry|October 20, 2007
First gallamine-tacrine hybrid: design and characterization at cholinesterases and the M2 muscarinic receptorPaul W Elsinghorst, Julia S Cieslik, Klaus Mohr, et al.Expert Opinion on Investigational Drugs|January 31, 2008
Histone deacetylase inhibitors: possible implications for neurodegenerative disordersEric Hahnen, Jan Hauke, Christian Tränkle, et al.British Journal of Pharmacology|February 9, 2010
Rational design of dualsteric GPCR ligands: quests and promiseKlaus Mohr, Christian Tränkle, Evi Kostenis, et al.Current Topics in Medicinal Chemistry|November 2, 2011
A hydrazide linker strategy for heterobivalent compounds as ortho- and allosteric ligands of acetylcholine-binding proteinsPaul W Elsinghorst, Wolfgang Härtig, Daniela Gündisch, et al.Journal of Medicinal Chemistry|March 7, 2003
Systematic development of high affinity bis(ammonio)alkane-type allosteric enhancers of muscarinic ligand bindingMathias Muth, Wiebke Bender, Olaf Scharfenstein, et al.Neurochemical Research|April 5, 2003
Cooperative interactions at M2 muscarinic acetylcholine receptors: structure/activity relationships in stepwise shortened bispyridinium- and bis(ammonio)alkane-type allosteric modulatorsRalf Gilsbach, Maren Grossmüller, Vildan Alptüzün, et al.Bioorganic & Medicinal Chemistry Letters|January 3, 2006
6H,13H-Pyrazino[1,2-a;4,5-a']diindole analogs: probing the pharmacophore for allosteric ligands of muscarinic M2 receptorsDarius P Zlotos, Christian Tränkle, Aliaa Abdelrahman, et al.Bioorganic & Medicinal Chemistry|February 5, 2015
M2 Subtype preferring dibenzodiazepinone-type muscarinic receptor ligands: Effect of chemical homo-dimerization on orthosteric (and allosteric?) bindingMax Keller, Christian Tränkle, Xueke She, et al.Molecular Pharmacology|June 20, 2003
Interactions of orthosteric and allosteric ligands with [3H]dimethyl-W84 at the common allosteric site of muscarinic M2 receptorsChristian Tränkle, Oliver Weyand, Uta Voigtländer, et al.Pageof 5