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Christina Cherian

Showing results (1-10 of 19) with videos related to

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Molecular Genetics and Metabolism|November 7, 2007
A humanized mouse model for the reduced folate carrierDavid Patterson, Christine Graham, Christina Cherian, et al.
The Journal of Biological Chemistry|December 19, 2009
Identification of the minimal functional unit of the homo-oligomeric human reduced folate carrierZhanjun Hou, Christina Cherian, Joseph Drews, et al.
The Biochemical Journal|June 19, 2010
Substrate-specific binding and conformational changes involving Ser313 and transmembrane domain 8 of the human reduced folate carrier, as determined by site-directed mutagenesis and protein cross-linkingZhanjun Hou, Jianmei Wu, Jun Ye, et al.
Molecular Pharmacology|January 10, 2008
Role of lysine 411 in substrate carboxyl group binding to the human reduced folate carrier, as determined by site-directed mutagenesis and affinity inhibitionYijun Deng, Zhanjun Hou, Lei Wang, et al.
Journal of Medicinal Chemistry|August 6, 2008
Synthesis and discovery of high affinity folate receptor-specific glycinamide ribonucleotide formyltransferase inhibitors with antitumor activityYijun Deng, Yiqiang Wang, Christina Cherian, et al.
Journal of Medicinal Chemistry|January 17, 2012
Synthesis and biological activity of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl regioisomers as inhibitors of de novo purine biosynthesis with selectivity for cellular uptake by high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrierLei Wang, Christina Cherian, Sita Kugel Desmoulin, et al.
Journal of Medicinal Chemistry|October 12, 2013
Tumor-targeting with novel non-benzoyl 6-substituted straight chain pyrrolo[2,3-d]pyrimidine antifolates via cellular uptake by folate receptor α and inhibition of de novo purine nucleotide biosynthesisYiqiang Wang, Christina Cherian, Steven Orr, et al.
Journal of Medicinal Chemistry|April 18, 2009
Synthesis and biological activity of a novel series of 6-substituted thieno[2,3-d]pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transporter for cellular entryYijun Deng, Xilin Zhou, Sita Kugel Desmoulin, et al.
The Journal of Biological Chemistry|December 20, 2011
Identification and functional impact of homo-oligomers of the human proton-coupled folate transporterZhanjun Hou, Sita Kugel Desmoulin, Erika Etnyre, et al.
Molecular Pharmacology|June 29, 2012
Functional loss of the reduced folate carrier enhances the antitumor activities of novel antifolates with selective uptake by the proton-coupled folate transporterSita Kugel Desmoulin, Lei Wang, Lisa Polin, et al.
Pageof 2

Showing results (1-10 of 19) with videos related to

Sort By:
Pageof 2
Molecular Genetics and Metabolism|November 7, 2007
A humanized mouse model for the reduced folate carrierDavid Patterson, Christine Graham, Christina Cherian, et al.
The Journal of Biological Chemistry|December 19, 2009
Identification of the minimal functional unit of the homo-oligomeric human reduced folate carrierZhanjun Hou, Christina Cherian, Joseph Drews, et al.
The Biochemical Journal|June 19, 2010
Substrate-specific binding and conformational changes involving Ser313 and transmembrane domain 8 of the human reduced folate carrier, as determined by site-directed mutagenesis and protein cross-linkingZhanjun Hou, Jianmei Wu, Jun Ye, et al.
Molecular Pharmacology|January 10, 2008
Role of lysine 411 in substrate carboxyl group binding to the human reduced folate carrier, as determined by site-directed mutagenesis and affinity inhibitionYijun Deng, Zhanjun Hou, Lei Wang, et al.
Journal of Medicinal Chemistry|August 6, 2008
Synthesis and discovery of high affinity folate receptor-specific glycinamide ribonucleotide formyltransferase inhibitors with antitumor activityYijun Deng, Yiqiang Wang, Christina Cherian, et al.
Journal of Medicinal Chemistry|January 17, 2012
Synthesis and biological activity of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl regioisomers as inhibitors of de novo purine biosynthesis with selectivity for cellular uptake by high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrierLei Wang, Christina Cherian, Sita Kugel Desmoulin, et al.
Journal of Medicinal Chemistry|October 12, 2013
Tumor-targeting with novel non-benzoyl 6-substituted straight chain pyrrolo[2,3-d]pyrimidine antifolates via cellular uptake by folate receptor α and inhibition of de novo purine nucleotide biosynthesisYiqiang Wang, Christina Cherian, Steven Orr, et al.
Journal of Medicinal Chemistry|April 18, 2009
Synthesis and biological activity of a novel series of 6-substituted thieno[2,3-d]pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transporter for cellular entryYijun Deng, Xilin Zhou, Sita Kugel Desmoulin, et al.
The Journal of Biological Chemistry|December 20, 2011
Identification and functional impact of homo-oligomers of the human proton-coupled folate transporterZhanjun Hou, Sita Kugel Desmoulin, Erika Etnyre, et al.
Molecular Pharmacology|June 29, 2012
Functional loss of the reduced folate carrier enhances the antitumor activities of novel antifolates with selective uptake by the proton-coupled folate transporterSita Kugel Desmoulin, Lei Wang, Lisa Polin, et al.
Pageof 2