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Cancer Chemotherapy and Pharmacology
|
February 16, 2013
Therapeutic targeting malignant mesothelioma with a novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate via its selective uptake by the proton-coupled folate transporter
Christina Cherian, Sita Kugel Desmoulin, Lei Wang, et al.
Journal of Neurology
|
September 19, 2021
The phenotypic spectrum of KCNT1: a new family with variable epilepsy syndromes including mild focal epilepsy
Christina Cherian, Juan P Appendino, Setareh Ashtiani, et al.
Journal of Medicinal Chemistry
|
November 22, 2013
Discovery of 5-substituted pyrrolo[2,3-d]pyrimidine antifolates as dual-acting inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis: implications of inhibiting 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase to ampk activation and antitumor activity
Shermaine Mitchell-Ryan, Yiqiang Wang, Sudhir Raghavan, et al.
Molecular Pharmacology
|
September 24, 2011
Therapeutic targeting of a novel 6-substituted pyrrolo [2,3-d]pyrimidine thienoyl antifolate to human solid tumors based on selective uptake by the proton-coupled folate transporter
Sita Kugel Desmoulin, Lei Wang, Eric Hales, et al.
Journal of Medicinal Chemistry
|
January 21, 2010
Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entry
Lei Wang, Christina Cherian, Sita Kugel Desmoulin, et al.
Molecular Pharmacology
|
July 6, 2010
Targeting the proton-coupled folate transporter for selective delivery of 6-substituted pyrrolo[2,3-d]pyrimidine antifolate inhibitors of de novo purine biosynthesis in the chemotherapy of solid tumors
Sita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
June 2, 2012
Intestinal transport of aminopterin enantiomers in dogs and humans with psoriasis is stereoselective: evidence for a mechanism involving the proton-coupled folate transporter
Alan Menter, Breck Thrash, Christina Cherian, et al.
Journal of Medicinal Chemistry
|
September 2, 2011
Synthesis, biological, and antitumor activity of a highly potent 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibits β-glycinamide ribonucleotide formyltransferase
Lei Wang, Sita Kugel Desmoulin, Christina Cherian, et al.
Medrxiv : the Preprint Server for Health Sciences
|
March 3, 2023
Exome sequencing of 20,979 individuals with epilepsy reveals shared and distinct ultra-rare genetic risk across disorder subtypes
Siwei Chen, Bassel W Abou-Khalil, Zaid Afawi, et al.
Page
of 2
Search research articles
Search
Showing results (11-20 of 19) with videos related to
Sort By:
Page
of 2
You have reached the last page of results.
This site can display upto 19 results.
Cancer Chemotherapy and Pharmacology
|
February 16, 2013
Therapeutic targeting malignant mesothelioma with a novel 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate via its selective uptake by the proton-coupled folate transporter
Christina Cherian, Sita Kugel Desmoulin, Lei Wang, et al.
Journal of Neurology
|
September 19, 2021
The phenotypic spectrum of KCNT1: a new family with variable epilepsy syndromes including mild focal epilepsy
Christina Cherian, Juan P Appendino, Setareh Ashtiani, et al.
Journal of Medicinal Chemistry
|
November 22, 2013
Discovery of 5-substituted pyrrolo[2,3-d]pyrimidine antifolates as dual-acting inhibitors of glycinamide ribonucleotide formyltransferase and 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase in de novo purine nucleotide biosynthesis: implications of inhibiting 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase to ampk activation and antitumor activity
Shermaine Mitchell-Ryan, Yiqiang Wang, Sudhir Raghavan, et al.
Molecular Pharmacology
|
September 24, 2011
Therapeutic targeting of a novel 6-substituted pyrrolo [2,3-d]pyrimidine thienoyl antifolate to human solid tumors based on selective uptake by the proton-coupled folate transporter
Sita Kugel Desmoulin, Lei Wang, Eric Hales, et al.
Journal of Medicinal Chemistry
|
January 21, 2010
Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entry
Lei Wang, Christina Cherian, Sita Kugel Desmoulin, et al.
Molecular Pharmacology
|
July 6, 2010
Targeting the proton-coupled folate transporter for selective delivery of 6-substituted pyrrolo[2,3-d]pyrimidine antifolate inhibitors of de novo purine biosynthesis in the chemotherapy of solid tumors
Sita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
June 2, 2012
Intestinal transport of aminopterin enantiomers in dogs and humans with psoriasis is stereoselective: evidence for a mechanism involving the proton-coupled folate transporter
Alan Menter, Breck Thrash, Christina Cherian, et al.
Journal of Medicinal Chemistry
|
September 2, 2011
Synthesis, biological, and antitumor activity of a highly potent 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibits β-glycinamide ribonucleotide formyltransferase
Lei Wang, Sita Kugel Desmoulin, Christina Cherian, et al.
Medrxiv : the Preprint Server for Health Sciences
|
March 3, 2023
Exome sequencing of 20,979 individuals with epilepsy reveals shared and distinct ultra-rare genetic risk across disorder subtypes
Siwei Chen, Bassel W Abou-Khalil, Zaid Afawi, et al.
Page
of 2