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The Biochemical Journal
|
May 18, 2013
Convergent evolution of chromatin modification by structurally distinct enzymes: comparative enzymology of histone H3 Lys²⁷ methylation by human polycomb repressive complex 2 and vSET
Brooke M Swalm, Kenneth K Hallenbeck, Christina R Majer, et al.
Chemical Biology & Drug Design
|
May 14, 2011
Chemogenetic analysis of human protein methyltransferases
Victoria M Richon, Danielle Johnston, Christopher J Sneeringer, et al.
FEBS Letters
|
August 2, 2012
A687V EZH2 is a gain-of-function mutation found in lymphoma patients
Christina R Majer, Lei Jin, Margaret Porter Scott, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
December 20, 2019
Forced Self-Modification Assays as a Strategy to Screen MonoPARP Enzymes
Tim J Wigle, W David Church, Christina R Majer, et al.
Journal of Medicinal Chemistry
|
January 16, 2016
The Importance of Being Me: Magic Methyls, Methyltransferase Inhibitors, and the Discovery of Tazemetostat
Kevin W Kuntz, John E Campbell, Heike Keilhack, et al.
Cell Chemical Biology
|
July 18, 2020
In Vitro and Cellular Probes to Study PARP Enzyme Target Engagement
Tim J Wigle, Danielle J Blackwell, Laurie B Schenkel, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2016
Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666
Kenneth W Duncan, Nathalie Rioux, P Ann Boriack-Sjodin, et al.
Chembiochem : a European Journal of Chemical Biology
|
April 10, 2021
Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule
Tim J Wigle, Yue Ren, Jennifer R Molina, et al.
Nature Chemical Biology
|
October 2, 2012
A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells
Sarah K Knutson, Tim J Wigle, Natalie M Warholic, et al.
Cell Chemical Biology
|
March 11, 2021
A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants
Laurie B Schenkel, Jennifer R Molina, Kerren K Swinger, et al.
Page
of 2
Search research articles
Search
Showing results (1-10 of 13) with videos related to
Sort By:
Page
of 2
The Biochemical Journal
|
May 18, 2013
Convergent evolution of chromatin modification by structurally distinct enzymes: comparative enzymology of histone H3 Lys²⁷ methylation by human polycomb repressive complex 2 and vSET
Brooke M Swalm, Kenneth K Hallenbeck, Christina R Majer, et al.
Chemical Biology & Drug Design
|
May 14, 2011
Chemogenetic analysis of human protein methyltransferases
Victoria M Richon, Danielle Johnston, Christopher J Sneeringer, et al.
FEBS Letters
|
August 2, 2012
A687V EZH2 is a gain-of-function mutation found in lymphoma patients
Christina R Majer, Lei Jin, Margaret Porter Scott, et al.
SLAS Discovery : Advancing Life Sciences R & D
|
December 20, 2019
Forced Self-Modification Assays as a Strategy to Screen MonoPARP Enzymes
Tim J Wigle, W David Church, Christina R Majer, et al.
Journal of Medicinal Chemistry
|
January 16, 2016
The Importance of Being Me: Magic Methyls, Methyltransferase Inhibitors, and the Discovery of Tazemetostat
Kevin W Kuntz, John E Campbell, Heike Keilhack, et al.
Cell Chemical Biology
|
July 18, 2020
In Vitro and Cellular Probes to Study PARP Enzyme Target Engagement
Tim J Wigle, Danielle J Blackwell, Laurie B Schenkel, et al.
ACS Medicinal Chemistry Letters
|
March 18, 2016
Structure and Property Guided Design in the Identification of PRMT5 Tool Compound EPZ015666
Kenneth W Duncan, Nathalie Rioux, P Ann Boriack-Sjodin, et al.
Chembiochem : a European Journal of Chemical Biology
|
April 10, 2021
Targeted Degradation of PARP14 Using a Heterobifunctional Small Molecule
Tim J Wigle, Yue Ren, Jennifer R Molina, et al.
Nature Chemical Biology
|
October 2, 2012
A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells
Sarah K Knutson, Tim J Wigle, Natalie M Warholic, et al.
Cell Chemical Biology
|
March 11, 2021
A potent and selective PARP14 inhibitor decreases protumor macrophage gene expression and elicits inflammatory responses in tumor explants
Laurie B Schenkel, Jennifer R Molina, Kerren K Swinger, et al.
Page
of 2