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Journal of Medicinal Chemistry|December 19, 2009
Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinaseMatthew B Boxer, Jian-kang Jiang, Matthew G Vander Heiden, et al.Nature Methods|May 4, 2021
A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cellsYu Chen, Carlos A Tristan, Lu Chen, et al.Cell Reports|July 21, 2015
Genome-wide Analysis of Host-Plasmodium yoelii Interactions Reveals Regulators of the Type I Interferon ResponseJian Wu, Baowei Cai, Wenxiang Sun, et al.Human Molecular Genetics|November 2, 2013
High-content screening identifies small molecules that remove nuclear foci, affect MBNL distribution and CELF1 protein levels via a PKC-independent pathway in myotonic dystrophy cell linesAmi Ketley, Catherine Z Chen, Xin Li, et al.Biochemistry|July 8, 2009
Identification of aminothienopyridazine inhibitors of tau assembly by quantitative high-throughput screeningAlex Crowe, Wenwei Huang, Carlo Ballatore, et al.Environmental Health Perspectives|January 27, 2015
Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening studyNour Abdo, Menghang Xia, Chad C Brown, et al.Proceedings of the National Academy of Sciences of the United States of America|August 23, 2012
Identification of benzodiazepine Ro5-3335 as an inhibitor of CBF leukemia through quantitative high throughput screen against RUNX1-CBFβ interactionLea Cunningham, Steven Finckbeiner, R Katherine Hyde, et al.Plos One|November 14, 2013
A novel chordoma xenograft allows in vivo drug testing and reveals the importance of NF-κB signaling in chordoma biologyMatteo M Trucco, Ola Awad, Breelyn A Wilky, et al.Antimicrobial Agents and Chemotherapy|November 7, 2012
A class of tricyclic compounds blocking malaria parasite oocyst development and transmissionRichard T Eastman, Sittiporn Pattaradilokrat, Dipak K Raj, et al.Journal of Medicinal Chemistry|September 19, 2009
Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasisGanesha Rai, Ahmed A Sayed, Wendy A Lea, et al.Pageof 20