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Nature Medicine|April 26, 2011
EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapyJoachim Lupberger, Mirjam B Zeisel, Fei Xiao, et al.Gut|March 29, 2020
Targeting clinical epigenetic reprogramming for chemoprevention of metabolic and viral hepatocellular carcinomaFrank Jühling, Nourdine Hamdane, Emilie Crouchet, et al.Science Translational Medicine|June 3, 2026
Claudin-1 targeting suppresses tumor growth, invasion, and metastasis in patient-derived cholangiocarcinoma modelsZeina Nehme, Marion Muller, Jade Brochon, et al.Nature Biotechnology|March 24, 2015
Clearance of persistent hepatitis C virus infection in humanized mice using a claudin-1-targeting monoclonal antibodyLaurent Mailly, Fei Xiao, Joachim Lupberger, et al.Gastroenterology|March 6, 2019
HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic ResponseNourdine Hamdane, Frank Jühling, Emilie Crouchet, et al.Journal of Hepatology|October 29, 2022
Treatment of HCC with claudin-1-specific antibodies suppresses carcinogenic signaling and reprograms the tumor microenvironmentNatascha Roehlen, Marion Muller, Zeina Nehme, et al.Science Translational Medicine|December 21, 2022
A monoclonal antibody targeting nonjunctional claudin-1 inhibits fibrosis in patient-derived models by modulating cell plasticityNatascha Roehlen, Antonio Saviano, Houssein El Saghire, et al.Nature Communications|September 18, 2021
A human liver cell-based system modeling a clinical prognostic liver signature for therapeutic discoveryEmilie Crouchet, Simonetta Bandiera, Naoto Fujiwara, et al.Pageof 3