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Neuro-Degenerative Diseases|October 19, 2006
Assembly, trafficking and function of gamma-secretaseChristoph Kaether, Christian Haass, Harald Steiner
The Journal of Biological Chemistry|June 24, 2004
Co-expression of nicastrin and presenilin rescues a loss of function mutant of APH-1Dieter Edbauer, Christoph Kaether, Harald Steiner, et al.
The Journal of Cell Biology|December 8, 2004
A lipid boundary separates APP and secretases and limits amyloid beta-peptide generationChristoph Kaether, Christian Haass
The EMBO Journal|November 19, 2004
The presenilin C-terminus is required for ER-retention, nicastrin-binding and gamma-secretase activityChristoph Kaether, Anja Capell, Dieter Edbauer, et al.
The Journal of Biological Chemistry|November 7, 2003
Nicastrin interacts with gamma-secretase complex components via the N-terminal part of its transmembrane domainAnja Capell, Christoph Kaether, Dieter Edbauer, et al.
The Journal of Biological Chemistry|December 14, 2004
Gamma-secretase complex assembly within the early secretory pathwayAnja Capell, Dirk Beher, Stefan Prokop, et al.
The Journal of Cell Biology|July 31, 2002
Presenilin-1 affects trafficking and processing of betaAPP and is targeted in a complex with nicastrin to the plasma membraneChristoph Kaether, Sven Lammich, Dieter Edbauer, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|April 7, 2006
The GxGD motif of presenilin contributes to catalytic function and substrate identification of gamma-secretaseAya Yamasaki, Stefan Eimer, Masayasu Okochi, et al.
Trends in Cell Biology|December 24, 2002
Alzheimer disease gamma-secretase: a complex story of GxGD-type presenilin proteasesChristian Haass, Harald Steiner
Cold Spring Harbor Perspectives in Medicine|May 4, 2012
Trafficking and proteolytic processing of APPChristian Haass, Christoph Kaether, Gopal Thinakaran, et al.
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