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Investigational New Drugs
|
January 6, 2021
NT157, an IGF1R-IRS1/2 inhibitor, exhibits antineoplastic effects in pre-clinical models of chronic myeloid leukemia
Renata Scopim-Ribeiro, João Agostinho Machado-Neto, Christopher A Eide, et al.
Cancer Cell
|
July 18, 2006
Activating alleles of JAK3 in acute megakaryoblastic leukemia
Denise K Walters, Thomas Mercher, Ting-Lei Gu, et al.
Cancer Cell
|
September 24, 2019
Combining the Allosteric Inhibitor Asciminib with Ponatinib Suppresses Emergence of and Restores Efficacy against Highly Resistant BCR-ABL1 Mutants
Christopher A Eide, Matthew S Zabriskie, Samantha L Savage Stevens, et al.
Blood
|
February 26, 2025
A CEBPB/IL-1β/TNF-α feedback loop drives drug resistance to venetoclax and MDM2 inhibitors in monocytic leukemia
Basil Allen, Daniel Bottomly, Thomas Köhnke, et al.
Nature Communications
|
January 18, 2019
Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms
Haijiao Zhang, Samantha Savage, Anna Reister Schultz, et al.
Cancer Cell
|
November 3, 2009
AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance
Thomas O'Hare, William C Shakespeare, Xiaotian Zhu, et al.
Clinical and Translational Medicine
|
December 19, 2022
Loss of G0/G1 switch gene 2 (G0S2) promotes disease progression and drug resistance in chronic myeloid leukaemia (CML) by disrupting glycerophospholipid metabolism
Mayra A Gonzalez, Idaly M Olivas, Alfonso E Bencomo-Alvarez, et al.
Blood
|
August 2, 2019
Genomic landscape of neutrophilic leukemias of ambiguous diagnosis
Haijiao Zhang, Beth Wilmot, Daniel Bottomly, et al.
Blood Cancer Discovery
|
May 21, 2025
Genetic and Phenotypic correlates of clinical outcomes with Venetoclax in Acute Myeloid Leukemia: The GEN-PHEN-VEN study
Curtis A Lachowiez, Mael Heiblig, Gaspar Aspas Requena, et al.
Blood Neoplasia
|
April 20, 2026
Results of a phase 1 trial testing ruxolitinib plus venetoclax in patients with relapsed/refractory acute myeloid leukemia
Uma Borate, Cristina E Tognon, Yazan F Madanat, et al.
Page
of 9
Search research articles
Search
Showing results (71-80 of 83) with videos related to
Sort By:
Page
of 9
Investigational New Drugs
|
January 6, 2021
NT157, an IGF1R-IRS1/2 inhibitor, exhibits antineoplastic effects in pre-clinical models of chronic myeloid leukemia
Renata Scopim-Ribeiro, João Agostinho Machado-Neto, Christopher A Eide, et al.
Cancer Cell
|
July 18, 2006
Activating alleles of JAK3 in acute megakaryoblastic leukemia
Denise K Walters, Thomas Mercher, Ting-Lei Gu, et al.
Cancer Cell
|
September 24, 2019
Combining the Allosteric Inhibitor Asciminib with Ponatinib Suppresses Emergence of and Restores Efficacy against Highly Resistant BCR-ABL1 Mutants
Christopher A Eide, Matthew S Zabriskie, Samantha L Savage Stevens, et al.
Blood
|
February 26, 2025
A CEBPB/IL-1β/TNF-α feedback loop drives drug resistance to venetoclax and MDM2 inhibitors in monocytic leukemia
Basil Allen, Daniel Bottomly, Thomas Köhnke, et al.
Nature Communications
|
January 18, 2019
Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms
Haijiao Zhang, Samantha Savage, Anna Reister Schultz, et al.
Cancer Cell
|
November 3, 2009
AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance
Thomas O'Hare, William C Shakespeare, Xiaotian Zhu, et al.
Clinical and Translational Medicine
|
December 19, 2022
Loss of G0/G1 switch gene 2 (G0S2) promotes disease progression and drug resistance in chronic myeloid leukaemia (CML) by disrupting glycerophospholipid metabolism
Mayra A Gonzalez, Idaly M Olivas, Alfonso E Bencomo-Alvarez, et al.
Blood
|
August 2, 2019
Genomic landscape of neutrophilic leukemias of ambiguous diagnosis
Haijiao Zhang, Beth Wilmot, Daniel Bottomly, et al.
Blood Cancer Discovery
|
May 21, 2025
Genetic and Phenotypic correlates of clinical outcomes with Venetoclax in Acute Myeloid Leukemia: The GEN-PHEN-VEN study
Curtis A Lachowiez, Mael Heiblig, Gaspar Aspas Requena, et al.
Blood Neoplasia
|
April 20, 2026
Results of a phase 1 trial testing ruxolitinib plus venetoclax in patients with relapsed/refractory acute myeloid leukemia
Uma Borate, Cristina E Tognon, Yazan F Madanat, et al.
Page
of 9