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Frontiers in Genome Editing|October 29, 2021
Efficient Targeted Mutagenesis Mediated by CRISPR-Cas12a Ribonucleoprotein Complexes in MaizeShujie Dong, Yinping Lucy Qin, Christopher A Vakulskas, et al.Stem Cells Translational Medicine|May 23, 2023
Propensity of Patient-Derived iPSCs for Retinal Differentiation: Implications for Autologous Cell ReplacementJessica A Cooke, Andrew P Voigt, Michael A Collingwood, et al.Nature|April 9, 2025
Reprogramming site-specific retrotransposon activity to new DNA sitesChristopher W Fell, Lukas Villiger, Justin Lim, et al.Nature Medicine|January 30, 2019
Identification of preexisting adaptive immunity to Cas9 proteins in humansCarsten T Charlesworth, Priyanka S Deshpande, Daniel P Dever, et al.Nature Medicine|August 8, 2018
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cellsChristopher A Vakulskas, Daniel P Dever, Garrett R Rettig, et al.Science Translational Medicine|June 17, 2021
Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell diseaseAnnalisa Lattanzi, Joab Camarena, Premanjali Lahiri, et al.Nature Medicine|March 19, 2021
Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cellsM Kyle Cromer, Joab Camarena, Renata M Martin, et al.Blood Advances|December 14, 2023
Genetically corrected RAG2-SCID human hematopoietic stem cells restore V(D)J-recombinase and rescue lymphoid deficiencyMara Pavel-Dinu, Cameron L Gardner, Yusuke Nakauchi, et al.Nature Communications|June 24, 2021
AsCas12a ultra nuclease facilitates the rapid generation of therapeutic cell medicinesLiyang Zhang, John A Zuris, Ramya Viswanathan, et al.Nature Biotechnology|November 24, 2022
Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrasesMatthew T N Yarnall, Eleonora I Ioannidi, Cian Schmitt-Ulms, et al.Pageof 5