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Developmental Cell|September 17, 2021
Endosomal trafficking and DNA damage checkpoint kinases dictate survival to replication stress by regulating amino acid uptake and protein synthesisArta Ajazi, Christopher Bruhn, Ghadeer Shubassi, et al.
Nature Communications|August 21, 2020
The Rad53<sup>CHK1/CHK2</sup>-Spt21<sup>NPAT</sup> and Tel1<sup>ATM</sup> axes couple glucose tolerance to histone dosage and subtelomeric silencingChristopher Bruhn, Arta Ajazi, Elisa Ferrari, et al.
Molecular Cell|June 27, 2017
PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage ResponseElisa Ferrari, Christopher Bruhn, Marta Peretti, et al.
Cell Death & Disease|March 2, 2026
Targeting the FNIP2-SERCA2b axis improves metabolic and mitochondrial defects in Ataxia TelangiectasiaMaria Vinciguerra, Catiana El Kharef, Christopher Bruhn, et al.
Expert Opinion on Drug Metabolism & Toxicology|November 23, 2023
In-depth mechanistic analysis including high-throughput RNA sequencing in the prediction of functional and structural cardiotoxicants using hiPSC cardiomyocytesAlicia Rosell-Hidalgo, Christopher Bruhn, Emma Shardlow, et al.
Nature Communications|December 21, 2013
Poly(ADP-ribose) binding to Chk1 at stalled replication forks is required for S-phase checkpoint activationWooKee Min, Christopher Bruhn, Paulius Grigaravicius, et al.
The EMBO Journal|March 31, 2015
Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletionJitendra K Meena, Aurora Cerutti, Christine Beichler, et al.
Nucleic Acids Research|October 5, 2017
Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivoHarald Schuhwerk, Christopher Bruhn, Kanstantsin Siniuk, et al.
Nucleic Acids Research|March 19, 2025
DNA damage response regulator ATR licenses PINK1-mediated mitophagyChristian Marx, Xiaobing Qing, Yamin Gong, et al.
Nature Communications|September 25, 2020
ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migrationGururaj Rao Kidiyoor, Qingsen Li, Giulia Bastianello, et al.
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