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Bioorganic & Medicinal Chemistry|May 28, 2011
Extraction of tacit knowledge from large ADME data sets via pairwise analysisChristopher E Keefer, George Chang, Gregory W KauffmanBioorganic & Medicinal Chemistry|November 15, 2016
A multi-endpoint matched molecular pair (MMP) analysis of 6-membered heterocyclesGeorge Chang, Kim Huard, Gregory W Kauffman, et al.Journal of Chemical Information and Modeling|January 25, 2013
Interpretable, probability-based confidence metric for continuous quantitative structure-activity relationship modelsChristopher E Keefer, Gregory W Kauffman, Rishi Raj GuptaMedchemcomm|August 16, 2018
The use of matched molecular series networks for cross target structure activity relationship translation and potency predictionChristopher E Keefer, George ChangJournal of Medicinal Chemistry|July 27, 2013
Evaluating the differences in cycloalkyl ether metabolism using the design parameter "lipophilic metabolism efficiency" (LipMetE) and a matched molecular pairs analysisAntonia F Stepan, Gregory W Kauffman, Christopher E Keefer, et al.Journal of Chemical Information and Modeling|December 1, 2018
In-Silico Extraction of Design Ideas Using MMPA-by-QSAR and its Application on ADME EndpointsAlexios Koutsoukas, George Chang, Christopher E KeeferDrug Metabolism Letters|September 16, 2011
Systematic and pairwise analysis of the effects of aromatic halogenation and trifluoromethyl substitution on human liver microsomal clearanceHao Sun, Christopher E Keefer, Dennis O ScottThe Journal of Biological Chemistry|December 31, 2003
Physicochemical features of the HERG channel drug binding siteDavid Fernandez, Azad Ghanta, Gregory W Kauffman, et al.Expert Opinion on Therapeutic Patents|July 24, 2013
Novel γ-secretase modulators for the treatment of Alzheimer's disease: a review focusing on patents from 2010 to 2012Martin Pettersson, Antonia F Stepan, Gregory W Kauffman, et al.Journal of Medicinal Chemistry|May 27, 2016
Quantitative Assessment of the Impact of Fluorine Substitution on P-Glycoprotein (P-gp) Mediated Efflux, Permeability, Lipophilicity, and Metabolic StabilityMartin Pettersson, Xinjun Hou, Max Kuhn, et al.Pageof 8