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SLAS Discovery : Advancing Life Sciences R & D
|
May 9, 2024
Creating a more strategic small molecule biophysical hit characterization workflow
Christopher Fotsch, Debaleena Basu, Ryan Case, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 10, 2011
Design and synthesis of novel amide AKT1 inhibitors with selectivity over CDK2
Kate S Ashton, David J St Jean, Steve F Poon, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Synthesis and Evaluation of the Metabolites of AMG 221, a Clinical Candidate for the Treatment of Type 2 Diabetes
Aiwen Li, Chester C Yuan, David Chow, et al.
Journal of Medicinal Chemistry
|
February 3, 2007
2-(S)-phenethylaminothiazolones as potent, orally efficacious inhibitors of 11beta-hydroxysteriod dehydrogenase type 1
David J St Jean, Chester Yuan, Eric A Bercot, et al.
Chemical Biology & Drug Design
|
December 12, 2007
Structural characterization and pharmacodynamic effects of an orally active 11beta-hydroxysteroid dehydrogenase type 1 inhibitor
Clarence Hale, Murielle Véniant, Zhulun Wang, et al.
Journal of Medicinal Chemistry
|
December 28, 2002
Structure-activity relationship of (1-aryl-2-piperazinylethyl)piperazines: antagonists for the AGRP/melanocortin receptor binding
Premilla N Arasasingham, Christopher Fotsch, Xiaohu Ouyang, et al.
Journal of Medicinal Chemistry
|
October 20, 2009
Discovery and optimization of substituted 1-(1-phenyl-1H-pyrazol-3-yl)methanamines as potent and efficacious type II calcimimetics
Steve F Poon, David J St Jean, Paul E Harrington, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 6, 2005
Synthesis and evaluation of thiazole carboxamides as vanilloid receptor 1 (TRPV1) antagonists
Ning Xi, Yunxin Bo, Elizabeth M Doherty, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 26, 2003
Design of a new peptidomimetic agonist for the melanocortin receptors based on the solution structure of the peptide ligand, Ac-Nle-cyclo[Asp-Pro-DPhe-Arg-Trp-Lys]-NH(2)
Christopher Fotsch, Duncan M Smith, Jeffrey A Adams, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
March 23, 2011
Discovery of a calcimimetic with differential effects on parathyroid hormone and calcitonin secretion
Charles Henley, Yuhua Yang, James Davis, et al.
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of 5
Search research articles
Search
Showing results (11-20 of 49) with videos related to
Sort By:
Page
of 5
SLAS Discovery : Advancing Life Sciences R & D
|
May 9, 2024
Creating a more strategic small molecule biophysical hit characterization workflow
Christopher Fotsch, Debaleena Basu, Ryan Case, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 10, 2011
Design and synthesis of novel amide AKT1 inhibitors with selectivity over CDK2
Kate S Ashton, David J St Jean, Steve F Poon, et al.
ACS Medicinal Chemistry Letters
|
June 6, 2014
Synthesis and Evaluation of the Metabolites of AMG 221, a Clinical Candidate for the Treatment of Type 2 Diabetes
Aiwen Li, Chester C Yuan, David Chow, et al.
Journal of Medicinal Chemistry
|
February 3, 2007
2-(S)-phenethylaminothiazolones as potent, orally efficacious inhibitors of 11beta-hydroxysteriod dehydrogenase type 1
David J St Jean, Chester Yuan, Eric A Bercot, et al.
Chemical Biology & Drug Design
|
December 12, 2007
Structural characterization and pharmacodynamic effects of an orally active 11beta-hydroxysteroid dehydrogenase type 1 inhibitor
Clarence Hale, Murielle Véniant, Zhulun Wang, et al.
Journal of Medicinal Chemistry
|
December 28, 2002
Structure-activity relationship of (1-aryl-2-piperazinylethyl)piperazines: antagonists for the AGRP/melanocortin receptor binding
Premilla N Arasasingham, Christopher Fotsch, Xiaohu Ouyang, et al.
Journal of Medicinal Chemistry
|
October 20, 2009
Discovery and optimization of substituted 1-(1-phenyl-1H-pyrazol-3-yl)methanamines as potent and efficacious type II calcimimetics
Steve F Poon, David J St Jean, Paul E Harrington, et al.
Bioorganic & Medicinal Chemistry Letters
|
October 6, 2005
Synthesis and evaluation of thiazole carboxamides as vanilloid receptor 1 (TRPV1) antagonists
Ning Xi, Yunxin Bo, Elizabeth M Doherty, et al.
Bioorganic & Medicinal Chemistry Letters
|
June 26, 2003
Design of a new peptidomimetic agonist for the melanocortin receptors based on the solution structure of the peptide ligand, Ac-Nle-cyclo[Asp-Pro-DPhe-Arg-Trp-Lys]-NH(2)
Christopher Fotsch, Duncan M Smith, Jeffrey A Adams, et al.
The Journal of Pharmacology and Experimental Therapeutics
|
March 23, 2011
Discovery of a calcimimetic with differential effects on parathyroid hormone and calcitonin secretion
Charles Henley, Yuhua Yang, James Davis, et al.
Page
of 5