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Christopher Fotsch

Showing results (31-40 of 49) with videos related to

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Journal of Medicinal Chemistry|April 19, 2008
2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 miceLars Johansson, Christopher Fotsch, Michael D Bartberger, et al.
Bioorganic & Medicinal Chemistry Letters|October 15, 2013
The optimization of aminooxadiazoles as orally active inhibitors of Cdc7Paul E Harrington, Matthew P Bourbeau, Christopher Fotsch, et al.
Bioorganic & Medicinal Chemistry Letters|October 9, 2007
The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitorsChester Yuan, David J St Jean, Qingyian Liu, et al.
Journal of Medicinal Chemistry|March 12, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 3. Structure-activity relationships within the aryl carbinol region of the N-arylsulfonamido-N'-arylpiperazine seriesNobuko Nishimura, Mark H Norman, Longbin Liu, et al.
Bioorganic & Medicinal Chemistry Letters|February 9, 2006
A new class of bradykinin 1 receptor antagonists containing the piperidine acetic acid tetralin coreChristopher Fotsch, Gloria Biddlecome, Kaustav Biswas, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1Lewis D Pennington, Kelvin K C Sham, Alexander J Pickrell, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone CorePaul E Harrington, Michael D Croghan, Christopher Fotsch, et al.
Bioorganic & Medicinal Chemistry Letters|February 9, 2010
Azole-based inhibitors of AKT/PKB for the treatment of cancerQingping Zeng, John G Allen, Matthew P Bourbeau, et al.
Journal of Medicinal Chemistry|December 5, 2008
Further studies with the 2-amino-1,3-thiazol-4(5H)-one class of 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: reducing pregnane X receptor activity and exploring activity in a monkey pharmacodynamic modelChristopher Fotsch, Michael D Bartberger, Eric A Bercot, et al.
Bioorganic & Medicinal Chemistry Letters|November 23, 2011
Quinolinone-based agonists of S1P₁: use of a N-scan SAR strategy to optimize in vitro and in vivo activityLewis D Pennington, Michael D Croghan, Kelvin K C Sham, et al.
Pageof 5

Showing results (31-40 of 49) with videos related to

Sort By:
Pageof 5
Journal of Medicinal Chemistry|April 19, 2008
2-amino-1,3-thiazol-4(5H)-ones as potent and selective 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: enzyme-ligand co-crystal structure and demonstration of pharmacodynamic effects in C57Bl/6 miceLars Johansson, Christopher Fotsch, Michael D Bartberger, et al.
Bioorganic & Medicinal Chemistry Letters|October 15, 2013
The optimization of aminooxadiazoles as orally active inhibitors of Cdc7Paul E Harrington, Matthew P Bourbeau, Christopher Fotsch, et al.
Bioorganic & Medicinal Chemistry Letters|October 9, 2007
The discovery of 2-anilinothiazolones as 11beta-HSD1 inhibitorsChester Yuan, David J St Jean, Qingyian Liu, et al.
Journal of Medicinal Chemistry|March 12, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 3. Structure-activity relationships within the aryl carbinol region of the N-arylsulfonamido-N'-arylpiperazine seriesNobuko Nishimura, Mark H Norman, Longbin Liu, et al.
Bioorganic & Medicinal Chemistry Letters|February 9, 2006
A new class of bradykinin 1 receptor antagonists containing the piperidine acetic acid tetralin coreChristopher Fotsch, Gloria Biddlecome, Kaustav Biswas, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
4-Methoxy-N-[2-(trifluoromethyl)biphenyl-4-ylcarbamoyl]nicotinamide: A Potent and Selective Agonist of S1P1Lewis D Pennington, Kelvin K C Sham, Alexander J Pickrell, et al.
ACS Medicinal Chemistry Letters|June 6, 2014
Optimization of a Potent, Orally Active S1P1 Agonist Containing a Quinolinone CorePaul E Harrington, Michael D Croghan, Christopher Fotsch, et al.
Bioorganic & Medicinal Chemistry Letters|February 9, 2010
Azole-based inhibitors of AKT/PKB for the treatment of cancerQingping Zeng, John G Allen, Matthew P Bourbeau, et al.
Journal of Medicinal Chemistry|December 5, 2008
Further studies with the 2-amino-1,3-thiazol-4(5H)-one class of 11beta-hydroxysteroid dehydrogenase type 1 inhibitors: reducing pregnane X receptor activity and exploring activity in a monkey pharmacodynamic modelChristopher Fotsch, Michael D Bartberger, Eric A Bercot, et al.
Bioorganic & Medicinal Chemistry Letters|November 23, 2011
Quinolinone-based agonists of S1P₁: use of a N-scan SAR strategy to optimize in vitro and in vivo activityLewis D Pennington, Michael D Croghan, Kelvin K C Sham, et al.
Pageof 5