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Christopher Fotsch

Showing results (41-50 of 49) with videos related to

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Journal of Medicinal Chemistry|May 15, 2010
Discovery of a potent, orally active 11beta-hydroxysteroid dehydrogenase type 1 inhibitor for clinical study: identification of (S)-2-((1S,2S,4R)-bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one (AMG 221)Murielle M Véniant, Clarence Hale, Randall W Hungate, et al.
Bioorganic & Medicinal Chemistry Letters|August 17, 2010
The discovery of an orally efficacious positive allosteric modulator of the calcium sensing receptor containing a dibenzylamine corePaul E Harrington, David J St Jean, Jeffrey Clarine, et al.
Bioorganic & Medicinal Chemistry Letters|April 26, 2011
3-Oxo-2-piperazinyl acetamides as potent bradykinin B1 receptor antagonists for the treatment of pain and inflammationJian Jeffrey Chen, Thomas Nguyen, Derin C D'Amico, et al.
Journal of Medicinal Chemistry|January 11, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 1. Discovery of a novel tool compound for in vivo proof-of-conceptKate S Ashton, Kristin L Andrews, Marian C Bryan, et al.
Journal of Medicinal Chemistry|January 11, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profilesDavid J St Jean, Kate S Ashton, Michael D Bartberger, et al.
Journal of Medicinal Chemistry|January 25, 2007
Identification of a nonpeptidic and conformationally restricted bradykinin B1 receptor antagonist with anti-inflammatory activityDerin C D'Amico, Toshi Aya, Jason Human, et al.
Nature|November 15, 2013
Antidiabetic effects of glucokinase regulatory protein small-molecule disruptorsDavid J Lloyd, David J St Jean, Robert J M Kurzeja, et al.
Journal of Medicinal Chemistry|April 6, 2007
Potent nonpeptide antagonists of the bradykinin B1 receptor: structure-activity relationship studies with novel diaminochroman carboxamidesKaustav Biswas, Aiwen Li, Jian Jeffrey Chen, et al.
Journal of Medicinal Chemistry|November 10, 2015
Discovery and Structure-Guided Optimization of Diarylmethanesulfonamide Disrupters of Glucokinase-Glucokinase Regulatory Protein (GK-GKRP) Binding: Strategic Use of a N → S (nN → σ*S-X) Interaction for Conformational ConstraintLewis D Pennington, Michael D Bartberger, Michael D Croghan, et al.
Pageof 5

Showing results (41-50 of 49) with videos related to

Sort By:
Pageof 5
You have reached the last page of results.This site can display upto 49 results.
Journal of Medicinal Chemistry|May 15, 2010
Discovery of a potent, orally active 11beta-hydroxysteroid dehydrogenase type 1 inhibitor for clinical study: identification of (S)-2-((1S,2S,4R)-bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one (AMG 221)Murielle M Véniant, Clarence Hale, Randall W Hungate, et al.
Bioorganic & Medicinal Chemistry Letters|August 17, 2010
The discovery of an orally efficacious positive allosteric modulator of the calcium sensing receptor containing a dibenzylamine corePaul E Harrington, David J St Jean, Jeffrey Clarine, et al.
Bioorganic & Medicinal Chemistry Letters|April 26, 2011
3-Oxo-2-piperazinyl acetamides as potent bradykinin B1 receptor antagonists for the treatment of pain and inflammationJian Jeffrey Chen, Thomas Nguyen, Derin C D'Amico, et al.
Journal of Medicinal Chemistry|January 11, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 1. Discovery of a novel tool compound for in vivo proof-of-conceptKate S Ashton, Kristin L Andrews, Marian C Bryan, et al.
Journal of Medicinal Chemistry|January 11, 2014
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profilesDavid J St Jean, Kate S Ashton, Michael D Bartberger, et al.
Journal of Medicinal Chemistry|January 25, 2007
Identification of a nonpeptidic and conformationally restricted bradykinin B1 receptor antagonist with anti-inflammatory activityDerin C D'Amico, Toshi Aya, Jason Human, et al.
Nature|November 15, 2013
Antidiabetic effects of glucokinase regulatory protein small-molecule disruptorsDavid J Lloyd, David J St Jean, Robert J M Kurzeja, et al.
Journal of Medicinal Chemistry|April 6, 2007
Potent nonpeptide antagonists of the bradykinin B1 receptor: structure-activity relationship studies with novel diaminochroman carboxamidesKaustav Biswas, Aiwen Li, Jian Jeffrey Chen, et al.
Journal of Medicinal Chemistry|November 10, 2015
Discovery and Structure-Guided Optimization of Diarylmethanesulfonamide Disrupters of Glucokinase-Glucokinase Regulatory Protein (GK-GKRP) Binding: Strategic Use of a N → S (nN → σ*S-X) Interaction for Conformational ConstraintLewis D Pennington, Michael D Bartberger, Michael D Croghan, et al.
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