Showing results (1-10 of 402) with videos related to

Sort By:
Pageof 41
Trends in Pharmacological Sciences|August 8, 2006
Allosteric agonists of 7TM receptors: expanding the pharmacological toolboxChristopher J Langmead, Arthur Christopoulos
British Journal of Pharmacology|February 28, 2013
Supra-physiological efficacy at GPCRs: superstition or super agonists?Christopher J Langmead, Arthur Christopoulos
Current Opinion in Cell Biology|April 1, 2014
Functional and structural perspectives on allosteric modulation of GPCRsChristopher J Langmead, Arthur Christopoulos
Biochemical Pharmacology|December 30, 2023
Ligand-directed biased agonism at human histamine H3 receptor isoforms across Gαi/o- and β-arrestin2-mediated pathwaysSabrina N Rahman, Faissal Imhaouran, Rob Leurs, et al.
Molecular Pharmacology|July 28, 2016
Molecular Mechanisms of Action of M5 Muscarinic Acetylcholine Receptor Allosteric ModulatorsAlice E Berizzi, Patrick R Gentry, Patricia Rueda, et al.
ACS Chemical Neuroscience|January 26, 2023
Structural and Molecular Determinants for Isoform Bias at Human Histamine H3 Receptor IsoformsSabrina N Rahman, Daniel A McNaught-Flores, Yara Huppelschoten, et al.
Molecular Pharmacology|May 26, 2007
Structure-function studies of allosteric agonism at M2 muscarinic acetylcholine receptorsLauren T May, Vimesh A Avlani, Christopher J Langmead, et al.
ACS Chemical Neuroscience|April 24, 2018
Structure-Activity Relationships of Pan-Gαq/11 Coupled Muscarinic Acetylcholine Receptor Positive Allosteric ModulatorsAlice E Berizzi, Aaron M Bender, Craig W Lindsley, et al.
Molecular Pharmacology|October 7, 2005
Probing the molecular mechanism of interaction between 4-n-butyl-1-[4-(2-methylphenyl)-4-oxo-1-butyl]-piperidine (AC-42) and the muscarinic M(1) receptor: direct pharmacological evidence that AC-42 is an allosteric agonistChristopher J Langmead, Victoria A H Fry, Ian T Forbes, et al.
Molecular Pharmacology|August 6, 2015
Label-Free Kinetics: Exploiting Functional Hemi-Equilibrium to Derive Rate Constants for Muscarinic Receptor AntagonistsDarren M Riddy, Celine Valant, Patricia Rueda, et al.
Pageof 41