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European Journal of Medicinal Chemistry|April 26, 2020
Substituted oxindol-3-ylidenes as AMP-activated protein kinase (AMPK) inhibitorsChristopher J Matheson, Kimberly A Casalvieri, Donald S Backos, et al.IUBMB Life|May 20, 2015
RSK3: A regulator of pathological cardiac remodelingEliana C Martinez, Catherine L Passariello, Jinliang Li, et al.Molecular Cancer Therapeutics|January 2, 2016
Structure-Based Screen Identification of a Mammalian Ste20-like Kinase 4 (MST4) Inhibitor with Therapeutic Potential for Pituitary TumorsWeipeng Xiong, Christopher J Matheson, Mei Xu, et al.ACS Chemical Biology|January 9, 2016
A WEE1 Inhibitor Analog of AZD1775 Maintains Synergy with Cisplatin and Demonstrates Reduced Single-Agent Cytotoxicity in Medulloblastoma CellsChristopher J Matheson, Sujatha Venkataraman, Vladimir Amani, et al.Chemistry (Weinheim an Der Bergstrasse, Germany)|January 25, 2014
Trifluoroacetic acid in 2,2,2-trifluoroethanol facilitates S(N)Ar reactions of heterocycles with arylaminesBenoit Carbain, Christopher R Coxon, Honorine Lebraud, et al.Organic & Biomolecular Chemistry|November 12, 2013
Model system for irreversible inhibition of Nek2: thiol addition to ethynylpurines and related substituted heterocyclesHonorine Lebraud, Christopher R Coxon, Victoria S Archard, et al.European Journal of Pharmacology|May 10, 2016
A novel substituted aminoquinoline selectively targets voltage-sensitive sodium channel isoforms and NMDA receptor subtypes and alleviates chronic inflammatory and neuropathic painBoris Tabakoff, Wenhua Ren, Lauren Vanderlinden, et al.Oncotarget|November 12, 2016
Structure-guided design of purine-based probes for selective Nek2 inhibitionChristopher R Coxon, Christopher Wong, Richard Bayliss, et al.RSC Medicinal Chemistry|January 22, 2021
2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinaseChristopher J Matheson, Christopher R Coxon, Richard Bayliss, et al.The Journal of Biological Chemistry|April 24, 2014
Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migrationAaron B Krueger, David J Drasin, Wendy A Lea, et al.Pageof 3