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Biorxiv : the Preprint Server for Biology|July 2, 2024
Targeted Degradation of CDK9 Potently Disrupts the MYC Transcriptional NetworkMohammed A Toure, Keisuke Motoyama, Yichen Xiang, et al.International Journal of Radiation Oncology, Biology, Physics|August 3, 2021
Screening and Validation of Molecular Targeted RadiosensitizersHenning Willers, Xiao Pan, Nathalie Borgeaud, et al.Journal of Medicinal Chemistry|April 17, 2025
Structure-Guided Design of ISOX-DUAL-Based Degraders Targeting BRD4 and CBP/EP300: A Case of Degrader CollapseAnthony K Edmonds, Dimitrios-Ilias Balourdas, Graham P Marsh, et al.Blood Cancer Discovery|October 17, 2025
ID2 Suppresses Multiple Myeloma Cell Proliferation by Repressing the Activity of the Transcription Factor TCF3Mariateresa Fulciniti, Yao Yao, Tommaso Perini, et al.Cancer Discovery|September 26, 2024
DNAJB1-PRKACA Fusion Drives Fibrolamellar Liver Cancer through Impaired SIK Signaling and CRTC2/p300-Mediated Transcriptional ReprogrammingIlaria Gritti, Jinkai Wan, Vajira Weeresekara, et al.Molecular Cell|July 5, 2017
BET Bromodomain Proteins Function as Master Transcription Elongation Factors Independent of CDK9 RecruitmentGeorg E Winter, Andreas Mayer, Dennis L Buckley, et al.Nature Genetics|March 4, 2014
An epigenetic mechanism of resistance to targeted therapy in T cell acute lymphoblastic leukemiaBirgit Knoechel, Justine E Roderick, Kaylyn E Williamson, et al.Science Advances|February 6, 2021
Targeting oncoproteins with a positive selection assay for protein degradersVidyasagar Koduri, Leslie Duplaquet, Benjamin L Lampson, et al.Cancer Cell|March 10, 2021
A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulationGregory Lazarian, Shanye Yin, Elisa Ten Hacken, et al.Cell Reports|June 2, 2026
An orally active dual CBP/p300 degrader targets core dependencies of multiple myelomaPraveen Kumar Tiwari, Bomin Ku, Drew A Harrison, et al.Pageof 6