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Drug Metabolism and Disposition: the Biological Fate of Chemicals|April 3, 2009
Biotransformation of an alpha4beta2 nicotinic acetylcholine receptor partial agonist in sprague-dawley rats and the dispositional characterization of its N-carbamoyl glucuronide metaboliteChristopher L Shaffer, Tim F Ryder, Karthik Venkatakrishnan, et al.
Neuropharmacology|July 27, 2014
Enhancing ketamine translational pharmacology via receptor occupancy normalizationChristopher L Shaffer, Sarah M Osgood, Deborah L Smith, et al.
Expert Review of Anti-Infective Therapy|February 8, 2021
Antimicrobial prescribing for treatment of serious infections caused by Staphylococcus aureus and methicillin-resistant Staphylococcus aureus in pediatrics: an expert reviewSean N Avedissian, Nathanial J Rhodes, Christopher L Shaffer, et al.
Neuropharmacology|February 4, 2014
Phosphodiesterase 10A inhibitor MP-10 effects in primates: comparison with risperidone and mechanistic implicationsSubramaniam Uthayathas, Gunasingh J Masilamoni, Christopher L Shaffer, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 15, 2024
Radiolabel Uncovers Nonintuitive Metabolites of BIIB104: Novel Release of [14C]Cyanide from 2-Cyanothiophene and Subsequent Formation of [14C]ThiocyanateChungang Gu, Jiansheng Huang, Cathy Muste, et al.
Neuropharmacology|May 4, 2013
Therapeutic doses of antidepressants are projected not to inhibit human α4β2 nicotinic acetylcholine receptorsMark L Weber, Corry M Hofland, Christopher L Shaffer, et al.
Neuroreport|February 27, 2010
Glycine transporter inhibition reverses ketamine-induced working memory deficitsBrooke M Roberts, Christopher L Shaffer, Patricia A Seymour, et al.
Drug Metabolism Letters|April 10, 2009
Application of liquid chromatography-accelerator mass spectrometry (LC-AMS) to evaluate the metabolic profiles of a drug candidate in human urine and plasmaChandra Prakash, Christopher L Shaffer, Larry M Tremaine, et al.
Toxicologic Pathology|June 11, 2015
Drug-induced Skin Lesions in Cynomolgus Macaques Treated with Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric ModulatorsGopinath S Palanisamy, John M Marcek, Gregg D Cappon, et al.
Neurobiology of Learning and Memory|March 20, 2012
Phosphodiesterase type 5 (PDE5) inhibition improves object recognition memory: indications for central and peripheral mechanismsOlga A H Reneerkens, Kris Rutten, Sven Akkerman, et al.
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