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Christopher M Flores

Showing results (31-40 of 66) with videos related to

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Regulatory Toxicology and Pharmacology : RTP|August 7, 2022
First-in-human study to evaluate the safety, tolerability and pharmacokinetics of a novel analgesic and antipyretic drug with structural similarity to acetaminophenCathy K Gelotte, Amy M Vakil, Joris Berwaerts, et al.
The European Journal of Neuroscience|November 19, 2003
Potentiation of evoked calcitonin gene-related peptide release from oral mucosa: a potential basis for the pro-inflammatory effects of nicotineGregory O Dussor, Anthony S Leong, Nicholas B Gracia, et al.
Bioorganic & Medicinal Chemistry Letters|April 27, 2020
The discovery of diazetidinyl diamides as potent and reversible inhibitors of monoacylglycerol lipase (MAGL)Bin Zhu, Peter J Connolly, Sui-Po Zhang, et al.
Regulatory Toxicology and Pharmacology : RTP|August 25, 2023
JNJ-10450232 (NTM-006), A novel non-opioid with structural similarities to acetaminophen, produces relatively long-lasting analgesia after a single dose in patients undergoing 3rd molar extractionCathy K Gelotte, Amy M Vakil, Brenda A Zimmerman, et al.
Regulatory Toxicology and Pharmacology : RTP|April 13, 2025
The discovery and preclinical pharmacology of JNJ-10450232 (NTM-006), a centrally penetrant, non-opioid structural analog of acetaminophen with comparable analgesic and anti-pyretic properties but no evidence of hepatotoxicityChristopher M Flores, John R Carson, Ellen E Codd, et al.
Neuron|May 8, 2007
Attenuated cold sensitivity in TRPM8 null miceRaymond W Colburn, Mary Lou Lubin, Dennis J Stone, et al.
Regulatory Toxicology and Pharmacology : RTP|January 7, 2023
Preclinical safety assessment of JNJ-10450232 (NTM-006), a structural analog of acetaminophen, that does not cause hepatotoxicity at supratherapeutic dosesJunguo Zhou, Sandra De Jonghe, Ellen E Codd, et al.
Bioorganic & Medicinal Chemistry Letters|July 30, 2008
Discovery of piperidine carboxamide TRPV1 antagonistsWing S Cheung, Raul R Calvo, Brett A Tounge, et al.
Journal of Biomolecular Screening|April 13, 2012
Screening and characterization of human monoglyceride lipase active site inhibitors using orthogonal binding and functional assaysJosé C Clemente, Erica Nulton, Marina Nelen, et al.
Expert Opinion on Pharmacotherapy|June 16, 2012
Mechanistic and functional differentiation of tapentadol and tramadolRobert B Raffa, Helmut Buschmann, Thomas Christoph, et al.
Pageof 7

Showing results (31-40 of 66) with videos related to

Sort By:
Pageof 7
Regulatory Toxicology and Pharmacology : RTP|August 7, 2022
First-in-human study to evaluate the safety, tolerability and pharmacokinetics of a novel analgesic and antipyretic drug with structural similarity to acetaminophenCathy K Gelotte, Amy M Vakil, Joris Berwaerts, et al.
The European Journal of Neuroscience|November 19, 2003
Potentiation of evoked calcitonin gene-related peptide release from oral mucosa: a potential basis for the pro-inflammatory effects of nicotineGregory O Dussor, Anthony S Leong, Nicholas B Gracia, et al.
Bioorganic & Medicinal Chemistry Letters|April 27, 2020
The discovery of diazetidinyl diamides as potent and reversible inhibitors of monoacylglycerol lipase (MAGL)Bin Zhu, Peter J Connolly, Sui-Po Zhang, et al.
Regulatory Toxicology and Pharmacology : RTP|August 25, 2023
JNJ-10450232 (NTM-006), A novel non-opioid with structural similarities to acetaminophen, produces relatively long-lasting analgesia after a single dose in patients undergoing 3rd molar extractionCathy K Gelotte, Amy M Vakil, Brenda A Zimmerman, et al.
Regulatory Toxicology and Pharmacology : RTP|April 13, 2025
The discovery and preclinical pharmacology of JNJ-10450232 (NTM-006), a centrally penetrant, non-opioid structural analog of acetaminophen with comparable analgesic and anti-pyretic properties but no evidence of hepatotoxicityChristopher M Flores, John R Carson, Ellen E Codd, et al.
Neuron|May 8, 2007
Attenuated cold sensitivity in TRPM8 null miceRaymond W Colburn, Mary Lou Lubin, Dennis J Stone, et al.
Regulatory Toxicology and Pharmacology : RTP|January 7, 2023
Preclinical safety assessment of JNJ-10450232 (NTM-006), a structural analog of acetaminophen, that does not cause hepatotoxicity at supratherapeutic dosesJunguo Zhou, Sandra De Jonghe, Ellen E Codd, et al.
Bioorganic & Medicinal Chemistry Letters|July 30, 2008
Discovery of piperidine carboxamide TRPV1 antagonistsWing S Cheung, Raul R Calvo, Brett A Tounge, et al.
Journal of Biomolecular Screening|April 13, 2012
Screening and characterization of human monoglyceride lipase active site inhibitors using orthogonal binding and functional assaysJosé C Clemente, Erica Nulton, Marina Nelen, et al.
Expert Opinion on Pharmacotherapy|June 16, 2012
Mechanistic and functional differentiation of tapentadol and tramadolRobert B Raffa, Helmut Buschmann, Thomas Christoph, et al.
Pageof 7