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Journal of Molecular Biology|July 23, 2013
The effects of non-synonymous single nucleotide polymorphisms (nsSNPs) on protein-protein interactionsChristopher M Yates, Michael J E Sternberg
Journal of Molecular Biology|January 30, 2013
Proteins and domains vary in their tolerance of non-synonymous single nucleotide polymorphisms (nsSNPs)Christopher M Yates, Michael J E Sternberg
The Journal of Organic Chemistry|September 25, 2004
Enantioselective cyanation/Brook rearrangement/C-acylation reactions of acylsilanes catalyzed by chiral metal alkoxidesDavid A Nicewicz, Christopher M Yates, Jeffrey S Johnson
Journal of Molecular Biology|May 10, 2014
SuSPect: enhanced prediction of single amino acid variant (SAV) phenotype using network featuresChristopher M Yates, Ioannis Filippis, Lawrence A Kelley, et al.
Nature Protocols|May 8, 2015
The Phyre2 web portal for protein modeling, prediction and analysisLawrence A Kelley, Stefans Mezulis, Christopher M Yates, et al.
Bioorganic & Medicinal Chemistry Letters|June 28, 2017
Design and optimization of highly-selective, broad spectrum fungal CYP51 inhibitorsChristopher M Yates, Edward P Garvey, Sammy R Shaver, et al.
The Journal of Antimicrobial Chemotherapy|December 1, 2017
Fungal-specific Cyp51 inhibitor VT-1598 demonstrates in vitro activity against Candida and Cryptococcus species, endemic fungi, including Coccidioides species, Aspergillus species and Rhizopus arrhizusNathan P Wiederhold, Hoja P Patterson, Bich Hue Tran, et al.
Bioorganic & Medicinal Chemistry Letters|June 21, 2014
Design and optimization of highly-selective fungal CYP51 inhibitorsWilliam J Hoekstra, Edward P Garvey, William R Moore, et al.
ACS Medicinal Chemistry Letters|July 18, 2019
Development of Highly Selective Pyrimidine-Based Aldosterone Synthase (CYP11B2) InhibitorsSteven M Sparks, Dana P Danger, William J Hoekstra, et al.
Antimicrobial Agents and Chemotherapy|May 3, 2017
Crystal Structure of the New Investigational Drug Candidate VT-1598 in Complex with Aspergillus fumigatus Sterol 14α-Demethylase Provides Insights into Its Broad-Spectrum Antifungal ActivityTatiana Y Hargrove, Edward P Garvey, William J Hoekstra, et al.
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