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Christopher R Butler

Showing results (71-80 of 89) with videos related to

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Journal of Medicinal Chemistry|June 18, 2024
Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M<sub>4</sub> Muscarinic Acetylcholine ReceptorChristopher R Butler, Michael Popiolek, Laura A McAllister, et al.
Journal of Medicinal Chemistry|February 20, 2015
Discovery of a series of efficient, centrally efficacious BACE1 inhibitors through structure-based drug designChristopher R Butler, Michael A Brodney, Elizabeth M Beck, et al.
Journal of Medicinal Chemistry|March 3, 2018
Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of NeuroinflammationLaura A McAllister, Christopher R Butler, Scot Mente, et al.
Journal of Neurology, Neurosurgery, and Psychiatry|August 19, 2021
Practice effects in genetic frontotemporal dementia and at-risk individuals: a GENFI studyLinn Öijerstedt, Christin Andersson, Vesna Jelic, et al.
Journal of Neurology, Neurosurgery, and Psychiatry|March 16, 2021
MRI data-driven algorithm for the diagnosis of behavioural variant frontotemporal dementiaAna L Manera, Mahsa Dadar, John Cornelis Van Swieten, et al.
Bioorganic & Medicinal Chemistry Letters|May 20, 2015
Discovery of a novel Kv7 channel opener as a treatment for epilepsyJennifer E Davoren, Michelle M Claffey, Sheri L Snow, et al.
Journal of Neurology, Neurosurgery, and Psychiatry|June 12, 2019
Education modulates brain maintenance in presymptomatic frontotemporal dementiaStefano Gazzina, Mario Grassi, Enrico Premi, et al.
Journal of Medicinal Chemistry|March 18, 2015
Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitorsMichael A Brodney, Elizabeth M Beck, Christopher R Butler, et al.
Journal of Neurology, Neurosurgery, and Psychiatry|August 10, 2020
Early symptoms in symptomatic and preclinical genetic frontotemporal lobar degenerationTamara Paulo Tavares, Derek G V Mitchell, Kristy Kl Coleman, et al.
Journal of Neural Transmission (Vienna, Austria : 1996)|February 19, 2026
CSF protein biomarkers are associated with atrophy and symptom severity in genetic FTD: a GENFI studyAbbe Ullgren, Melissa Taheri Rydell, Sofia Bergström, et al.
Pageof 9

Showing results (71-80 of 89) with videos related to

Sort By:
Pageof 9
Journal of Medicinal Chemistry|June 18, 2024
Design and Synthesis of Clinical Candidate PF-06852231 (CVL-231): A Brain Penetrant, Selective, Positive Allosteric Modulator of the M<sub>4</sub> Muscarinic Acetylcholine ReceptorChristopher R Butler, Michael Popiolek, Laura A McAllister, et al.
Journal of Medicinal Chemistry|February 20, 2015
Discovery of a series of efficient, centrally efficacious BACE1 inhibitors through structure-based drug designChristopher R Butler, Michael A Brodney, Elizabeth M Beck, et al.
Journal of Medicinal Chemistry|March 3, 2018
Discovery of Trifluoromethyl Glycol Carbamates as Potent and Selective Covalent Monoacylglycerol Lipase (MAGL) Inhibitors for Treatment of NeuroinflammationLaura A McAllister, Christopher R Butler, Scot Mente, et al.
Journal of Neurology, Neurosurgery, and Psychiatry|August 19, 2021
Practice effects in genetic frontotemporal dementia and at-risk individuals: a GENFI studyLinn Öijerstedt, Christin Andersson, Vesna Jelic, et al.
Journal of Neurology, Neurosurgery, and Psychiatry|March 16, 2021
MRI data-driven algorithm for the diagnosis of behavioural variant frontotemporal dementiaAna L Manera, Mahsa Dadar, John Cornelis Van Swieten, et al.
Bioorganic & Medicinal Chemistry Letters|May 20, 2015
Discovery of a novel Kv7 channel opener as a treatment for epilepsyJennifer E Davoren, Michelle M Claffey, Sheri L Snow, et al.
Journal of Neurology, Neurosurgery, and Psychiatry|June 12, 2019
Education modulates brain maintenance in presymptomatic frontotemporal dementiaStefano Gazzina, Mario Grassi, Enrico Premi, et al.
Journal of Medicinal Chemistry|March 18, 2015
Utilizing structures of CYP2D6 and BACE1 complexes to reduce risk of drug-drug interactions with a novel series of centrally efficacious BACE1 inhibitorsMichael A Brodney, Elizabeth M Beck, Christopher R Butler, et al.
Journal of Neurology, Neurosurgery, and Psychiatry|August 10, 2020
Early symptoms in symptomatic and preclinical genetic frontotemporal lobar degenerationTamara Paulo Tavares, Derek G V Mitchell, Kristy Kl Coleman, et al.
Journal of Neural Transmission (Vienna, Austria : 1996)|February 19, 2026
CSF protein biomarkers are associated with atrophy and symptom severity in genetic FTD: a GENFI studyAbbe Ullgren, Melissa Taheri Rydell, Sofia Bergström, et al.
Pageof 9