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Molecules (Basel, Switzerland)|November 9, 2019
Towards the Development of an In vivo Chemical Probe for Cyclin G Associated Kinase (GAK)Christopher R M Asquith, James M Bennett, Lianyong Su, et al.
Journal of Medicinal Chemistry|April 12, 2019
Design of a Cyclin G Associated Kinase (GAK)/Epidermal Growth Factor Receptor (EGFR) Inhibitor Set to Interrogate the Relationship of EGFR and GAK in ChordomaChristopher R M Asquith, Kaleb M Naegeli, Michael P East, et al.
Molecules (Basel, Switzerland)|October 13, 2021
Synthesis and Evaluation of Novel 1,2,6-Thiadiazinone Kinase Inhibitors as Potent Inhibitors of Solid TumorsAndreas S Kalogirou, Michael P East, Tuomo Laitinen, et al.
Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine|January 27, 2019
Preclinical Evaluation of Benzazepine-Based PET Radioligands (R)- and (S)-11C-Me-NB1 Reveals Distinct Enantiomeric Binding Patterns and a Tightrope Walk Between GluN2B- and σ1-Receptor-Targeted PET ImagingAchi Haider, Adrienne Müller Herde, Stefanie D Krämer, et al.
Biorxiv : the Preprint Server for Biology|January 18, 2024
Discovery and Optimization of Narrow Spectrum Inhibitors of Tousled Like Kinase 2 (TLK2) Using Quantitative Structure Activity RelationshipsChristopher R M Asquith, Michael P East, Tuomo Laitinen, et al.
European Journal of Medicinal Chemistry|April 18, 2024
Discovery and optimization of narrow spectrum inhibitors of Tousled like kinase 2 (TLK2) using quantitative structure activity relationshipsChristopher R M Asquith, Michael P East, Tuomo Laitinen, et al.
Molecules (Basel, Switzerland)|May 23, 2018
1,2,6-Thiadiazinones as Novel Narrow Spectrum Calcium/Calmodulin-Dependent Protein Kinase Kinase 2 (CaMKK2) InhibitorsChristopher R M Asquith, Paulo H Godoi, Rafael M Couñago, et al.
Nature Chemical Biology|October 27, 2022
Small-molecule inhibition of the archetypal UbiB protein COQ8Nathan H Murray, Christopher R M Asquith, Zixiang Fang, et al.
Chemmedchem|October 27, 2017
Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated KinaseChristopher R M Asquith, Tuomo Laitinen, James M Bennett, et al.
Nature Communications|February 14, 2025
Structural insights into human brachyury DNA recognition and discovery of progressible binders for cancer therapyJoseph A Newman, Angeline E Gavard, Nergis Imprachim, et al.
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