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Nature|June 25, 2026
Base editing reveals an essential role for NANOG in human embryogenesisOliver J Bower, Ana E R Orsi, Riley McMahon, et al.Nature Biomedical Engineering|April 14, 2026
In vivo base editing rescues liver pathophysiology and peroxisome dysfunction in a mouse model of Zellweger spectrum disorderXin D Gao, Maximiliano Presa, Jordyn E Duby, et al.Cell|March 21, 2023
Human T cell generation is restored in CD3δ severe combined immunodeficiency through adenine base editingGrace E McAuley, Gloria Yiu, Patrick C Chang, et al.Nature Biomedical Engineering|November 28, 2024
Safer and efficient base editing and prime editing via ribonucleoproteins delivered through optimized lipid-nanoparticle formulationsRafał Hołubowicz, Samuel W Du, Jiin Felgner, et al.Cell|May 3, 2023
Massively parallel base editing to map variant effects in human hematopoiesisJorge D Martin-Rufino, Nicole Castano, Michael Pang, et al.Nature Medicine|January 14, 2025
In vivo base editing extends lifespan of a humanized mouse model of prion diseaseMeirui An, Jessie R Davis, Jonathan M Levy, et al.Nature Genetics|July 3, 2023
Potent and uniform fetal hemoglobin induction via base editingThiyagaraj Mayuranathan, Gregory A Newby, Ruopeng Feng, et al.Biorxiv : the Preprint Server for Biology|July 17, 2026
CD117 epitope-shielded hematopoietic stem cell transplantation with toxin-free conditioning and in vivo selection ameliorates a β-thalassemia modelRomina Marone, Rosalba Lepore, Kiriaki Paschoudi, et al.Nucleic Acids Research|September 24, 2024
Amphiphilic shuttle peptide delivers base editor ribonucleoprotein to correct the CFTR R553X mutation in well-differentiated airway epithelial cellsKatarina Kulhankova, Anna X Cheng, Soumba Traore, et al.Biorxiv : the Preprint Server for Biology|February 27, 2026
Mechanistic machine learning enables interpretable and generalizable prediction of prime editing outcomesAlvin Hsu, Peter J Chen, Angus H Li, et al.Pageof 31