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Methods in Enzymology|November 16, 2014
Determining the specificities of TALENs, Cas9, and other genome-editing enzymesVikram Pattanayak, John P Guilinger, David R Liu
Journal of the American Chemical Society|February 11, 2005
DNA-templated functional group transformations enable sequence-programmed synthesis using small-molecule reagentsKaori Sakurai, Thomas M Snyder, David R Liu
Nature Communications|June 29, 2017
Aptazyme-embedded guide RNAs enable ligand-responsive genome editing and transcriptional activationWeixin Tang, Johnny H Hu, David R Liu
Journal of the American Chemical Society|February 6, 2014
Identification of ligand-target pairs from combined libraries of small molecules and unpurified protein targets in cell lysatesLynn M McGregor, Tara Jain, David R Liu
Current Opinion in Chemical Biology|May 23, 2002
Recent advances in the in vitro evolution of nucleic acidsJoshua A Bittker, Kevin J Phillips, David R Liu
Nature Biotechnology|September 10, 2002
Nucleic acid evolution and minimization by nonhomologous random recombinationJoshua A Bittker, Brian V Le, David R Liu
Nature Biotechnology|April 29, 2014
Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modificationJohn P Guilinger, David B Thompson, David R Liu
Journal of the American Chemical Society|August 24, 2006
Binding and stability determinants of the PPARgamma nuclear receptor-coactivator interface as revealed by shotgun alanine scanning and in vivo selectionKevin J Phillips, Daniel M Rosenbaum, David R Liu
Nature Protocols|January 19, 2021
Precision genome editing using cytosine and adenine base editors in mammalian cellsTony P Huang, Gregory A Newby, David R Liu
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