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The Journal of Biological Chemistry|January 26, 2002
Substrate induced conformational changes in argininosuccinate synthetaseChristopher T Lemke, P Lynne Howell
Bioorganic & Medicinal Chemistry Letters|June 19, 2013
Discovery of novel P2 substituted 4-biaryl proline inhibitors of hepatitis C virus NS3 serine proteaseMurray D Bailey, Teddy Halmos, Christopher T Lemke
Acta Crystallographica. Section D, Biological Crystallography|November 28, 2002
S-SAD, Se-SAD and S/Se-SIRAS using Cu Kalpha radiation: why wait for synchrotron time?Christopher T Lemke, G David Smith, P Lynne Howell
Methods in Molecular Biology (Clifton, N.J.)|December 19, 2006
Substructure determination in multiwavelength anomalous diffraction, single anomalous diffraction, and single isomorphous replacement with anomalous scattering data using Shake-and-BakeG David Smith, Christopher T Lemke, P Lynne Howell
Acta Crystallographica. Section F, Structural Biology and Crystallization Communications|March 3, 2006
Crystallization and preliminary crystallographic analysis of an aminoglycoside kinase from Legionella pneumophilaChristopher T Lemke, Jiyoung Hwang, Bing Xiong, et al.
The Journal of Biological Chemistry|January 22, 2010
Structure of the antibiotic resistance factor spectinomycin phosphotransferase from Legionella pneumophilaDesiree H Fong, Christopher T Lemke, Jiyoung Hwang, et al.
Acta Crystallographica. Section D, Biological Crystallography|May 23, 2013
A novel inhibitor-binding site on the HIV-1 capsid N-terminal domain leads to improved crystallization via compound-mediated dimerizationChristopher T Lemke, Steve Titolo, Nathalie Goudreau, et al.
Journal of Medicinal Chemistry|October 23, 2013
Ligand bioactive conformation plays a critical role in the design of drugs that target the hepatitis C virus NS3 proteaseSteven R LaPlante, Herbert Nar, Christopher T Lemke, et al.
The Journal of Biological Chemistry|January 29, 2011
Combined X-ray, NMR, and kinetic analyses reveal uncommon binding characteristics of the hepatitis C virus NS3-NS4A protease inhibitor BI 201335Christopher T Lemke, Nathalie Goudreau, Songping Zhao, et al.
Bioorganic & Medicinal Chemistry Letters|June 19, 2013
Peptide backbone replacement of hepatitis C virus NS3 serine protease C-terminal cleavage product analogs: discovery of potent succinamide inhibitorsMurray D Bailey, Josée Bordeleau, Michel Garneau, et al.
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