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Journal of Cell Science|October 19, 2018
Nuclear entry and export of FIH are mediated by HIF1α and exportin1, respectivelyYihua Wang, Shan Zhong, Christopher J Schofield, et al.
The Biochemical Journal|March 3, 2006
Characterization of different isoforms of the HIF prolyl hydroxylase PHD1 generated by alternative initiationYa-Min Tian, David R Mole, Peter J Ratcliffe, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|September 27, 2006
Novel thioredoxin inhibitors paradoxically increase hypoxia-inducible factor-alpha expression but decrease functional transcriptional activity, DNA binding, and degradationDylan T Jones, Christopher W Pugh, Simon Wigfield, et al.
Molecular Aspects of Medicine|January 22, 2016
Pharmacological targeting of the HIF hydroxylases--A new field in medicine developmentMun Chiang Chan, James P Holt-Martyn, Christopher J Schofield, et al.
Life Science Alliance|February 1, 2023
Multi-level interaction between HIF and AHR transcriptional pathways in kidney carcinomaVéronique N Lafleur, Silvia Halim, Hani Choudhry, et al.
Plos Medicine|June 14, 2006
Mutation of von Hippel-Lindau tumour suppressor and human cardiopulmonary physiologyThomas G Smith, Jerome T Brooks, George M Balanos, et al.
The Journal of Clinical Investigation|January 31, 2020
Marked and rapid effects of pharmacological HIF-2α antagonism on hypoxic ventilatory controlXiaotong Cheng, Maria Prange-Barczynska, James W Fielding, et al.
Plos One|July 7, 2015
Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine BrainMun Chiang Chan, Onur Atasoylu, Emma Hodson, et al.
Cell Reports|November 17, 2022
Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signatureOlivia Lombardi, Ran Li, Silvia Halim, et al.
The Journal of Biological Chemistry|August 12, 2023
Comparative analysis of N-terminal cysteine dioxygenation and prolyl-hydroxylation as oxygen-sensing pathways in mammalian cellsYa-Min Tian, Philip Holdship, Trang Quynh To, et al.
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