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Cell Reports|December 14, 2023
Reduced lysosomal density in neuronal dendrites mediates deficits in synaptic plasticity in Huntington's diseaseJia-Hui Chen, Na Xu, Lei Qi, et al.Nature Methods|June 15, 2021
Metabolomic profiling of single enlarged lysosomesHongying Zhu, Qianqian Li, Tiepeng Liao, et al.Proceedings of the National Academy of Sciences of the United States of America|June 15, 2026
Lysosomal TMEM165 remodels calcium signaling to drive hypoxia adaptation and tumor progressionYu Zeng, Meiting Chen, Yu Cao, et al.Nature|January 28, 2021
A growth-factor-activated lysosomal K+ channel regulates Parkinson's pathologyJinhong Wie, Zhenjiang Liu, Haikun Song, et al.The EMBO Journal|January 28, 2025
Micropeptide hSPAR regulates glutamine levels and suppresses mammary tumor growth via a TRIM21-P27KIP1-mTOR axisYan Huang, Hua Lu, Yao Liu, et al.Nature Immunology|January 4, 2024
Carnosine regulation of intracellular pH homeostasis promotes lysosome-dependent tumor immunoevasionRonghui Yan, Pinggen Zhang, Shengqi Shen, et al.Immunity|March 13, 2024
Bile acids modified by the intestinal microbiota promote colorectal cancer growth by suppressing CD8+ T cell effector functionsJingjing Cong, Pianpian Liu, Zili Han, et al.American Journal of Human Genetics|December 29, 2015
Biallelic Mutations in UNC80 Cause Persistent Hypotonia, Encephalopathy, Growth Retardation, and Severe Intellectual DisabilityAsbjørg Stray-Pedersen, Jan-Maarten Cobben, Trine E Prescott, et al.The Journal of General Physiology|June 18, 2026
Stressed lysosome: A theoretical model of lysosomal pH regulation applied to stress conditionsSofia F Nazarova, Vadim A Alekhin, Vladislav V Pavlov, et al.Pageof 3