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Journal of Medicinal Chemistry
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April 14, 2021
Hydrophobic Pocket Occupation Design of Difluoro-Biphenyl-Diarylpyrimidines as Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors: from <i>N</i>-Alkylation to Methyl Hopping on the Pyrimidine Ring
Li Ding, Christophe Pannecouque, Erik De Clercq, et al.
Journal of Medicinal Chemistry
|
July 1, 2021
Improving Druggability of Novel Diarylpyrimidine NNRTIs by a Fragment-Based Replacement Strategy: From Biphenyl-DAPYs to Heteroaromatic-Biphenyl-DAPYs
Li Ding, Christophe Pannecouque, Erik De Clercq, et al.
Journal of Medicinal Chemistry
|
January 24, 2022
Discovery of Novel Pyridine-Dimethyl-Phenyl-DAPY Hybrids by Molecular Fusing of Methyl-Pyrimidine-DAPYs and Difluoro-Pyridinyl-DAPYs: Improving the Druggability toward High Inhibitory Activity, Solubility, Safety, and PK
Li Ding, Christophe Pannecouque, Erik De Clercq, et al.
European Journal of Medicinal Chemistry
|
April 30, 2021
Structure-based bioisosterism design of thio-benzoxazepinones as novel necroptosis inhibitors
Chunnian Xia, Zhengguang Yao, Lijuan Xu, et al.
Free Radical Research
|
December 29, 2025
6-Gingerol alleviates NNK-induced lung carcinogenesis by boosting antioxidation and reducing inflammation
Zhuo Qu, Yan Ding, Lei Zhang, et al.
Bioorganic Chemistry
|
June 4, 2023
Analysis on benzothiazole necroptosis inhibitors with chiral substitutions in the solvent-accessible region of RIP kinase domain
Hongming Shao, Lijuan Xu, Gechang Li, et al.
Chemical Reviews
|
May 11, 2017
Chalcone: A Privileged Structure in Medicinal Chemistry
Chunlin Zhuang, Wen Zhang, Chunquan Sheng, et al.
Nutrients
|
February 11, 2023
Dietary Phytochemicals as Potential Chemopreventive Agents against Tobacco-Induced Lung Carcinogenesis
Yan Ding, Ruilin Hou, Jianqiang Yu, et al.
RSC Medicinal Chemistry
|
December 23, 2022
Advanced approaches of developing targeted covalent drugs
Conghao Gai, Suzannah J Harnor, Shihao Zhang, et al.
Journal of Medicinal Chemistry
|
November 13, 2019
Ligand-Based Design of Nondimethylphenyl-Diarylpyrimidines with Improved Metabolic Stability, Safety, and Oral Pharmacokinetic Profiles
Yali Sang, Sheng Han, Christophe Pannecouque, et al.
Page
of 15
Search research articles
Search
Showing results (31-40 of 141) with videos related to
Sort By:
Page
of 15
Journal of Medicinal Chemistry
|
April 14, 2021
Hydrophobic Pocket Occupation Design of Difluoro-Biphenyl-Diarylpyrimidines as Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors: from <i>N</i>-Alkylation to Methyl Hopping on the Pyrimidine Ring
Li Ding, Christophe Pannecouque, Erik De Clercq, et al.
Journal of Medicinal Chemistry
|
July 1, 2021
Improving Druggability of Novel Diarylpyrimidine NNRTIs by a Fragment-Based Replacement Strategy: From Biphenyl-DAPYs to Heteroaromatic-Biphenyl-DAPYs
Li Ding, Christophe Pannecouque, Erik De Clercq, et al.
Journal of Medicinal Chemistry
|
January 24, 2022
Discovery of Novel Pyridine-Dimethyl-Phenyl-DAPY Hybrids by Molecular Fusing of Methyl-Pyrimidine-DAPYs and Difluoro-Pyridinyl-DAPYs: Improving the Druggability toward High Inhibitory Activity, Solubility, Safety, and PK
Li Ding, Christophe Pannecouque, Erik De Clercq, et al.
European Journal of Medicinal Chemistry
|
April 30, 2021
Structure-based bioisosterism design of thio-benzoxazepinones as novel necroptosis inhibitors
Chunnian Xia, Zhengguang Yao, Lijuan Xu, et al.
Free Radical Research
|
December 29, 2025
6-Gingerol alleviates NNK-induced lung carcinogenesis by boosting antioxidation and reducing inflammation
Zhuo Qu, Yan Ding, Lei Zhang, et al.
Bioorganic Chemistry
|
June 4, 2023
Analysis on benzothiazole necroptosis inhibitors with chiral substitutions in the solvent-accessible region of RIP kinase domain
Hongming Shao, Lijuan Xu, Gechang Li, et al.
Chemical Reviews
|
May 11, 2017
Chalcone: A Privileged Structure in Medicinal Chemistry
Chunlin Zhuang, Wen Zhang, Chunquan Sheng, et al.
Nutrients
|
February 11, 2023
Dietary Phytochemicals as Potential Chemopreventive Agents against Tobacco-Induced Lung Carcinogenesis
Yan Ding, Ruilin Hou, Jianqiang Yu, et al.
RSC Medicinal Chemistry
|
December 23, 2022
Advanced approaches of developing targeted covalent drugs
Conghao Gai, Suzannah J Harnor, Shihao Zhang, et al.
Journal of Medicinal Chemistry
|
November 13, 2019
Ligand-Based Design of Nondimethylphenyl-Diarylpyrimidines with Improved Metabolic Stability, Safety, and Oral Pharmacokinetic Profiles
Yali Sang, Sheng Han, Christophe Pannecouque, et al.
Page
of 15