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The Journal of Clinical Investigation|November 6, 2018
An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasionJohn D Klement, Amy V Paschall, Priscilla S Redd, et al.Oncogene|August 26, 2025
Slc7a5 promotes T cell anti-tumor immunity through sustaining cytotoxic T lymphocyte effector functionChunwan Lu, Liyan Liang, Yanmin Wu, et al.Plos Genetics|November 7, 2015
UFBP1, a Key Component of the Ufm1 Conjugation System, Is Essential for Ufmylation-Mediated Regulation of Erythroid DevelopmentYafei Cai, Wenhu Pi, Satish Sivaprakasam, et al.Journal for Immunotherapy of Cancer|January 12, 2022
G6PD functions as a metabolic checkpoint to regulate granzyme B expression in tumor-specific cytotoxic T lymphocytesChunwan Lu, Dafeng Yang, John D Klement, et al.Cell Reports|December 13, 2018
Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon TumorigenesisMohammed L Ibrahim, John D Klement, Chunwan Lu, et al.Cancer Cell|March 14, 2023
Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitmentJohn D Klement, Priscilla S Redd, Chunwan Lu, et al.Journal of Immunology (Baltimore, Md. : 1950)|July 3, 2015
H3K9 Trimethylation Silences Fas Expression To Confer Colon Carcinoma Immune Escape and 5-Fluorouracil ChemoresistanceAmy V Paschall, Dafeng Yang, Chunwan Lu, et al.Oncogene|March 30, 2022
H3K9me3 represses G6PD expression to suppress the pentose phosphate pathway and ROS production to promote human mesothelioma growthChunwan Lu, Dafeng Yang, John D Klement, et al.Cancers|January 21, 2022
Restoring FAS Expression via Lipid-Encapsulated FAS DNA Nanoparticle Delivery Is Sufficient to Suppress Colon Tumor Growth In VivoAlyssa D Merting, Dakota B Poschel, Chunwan Lu, et al.Oncotarget|March 26, 2016
NF-κB functions as a molecular link between tumor cells and Th1/Tc1 T cells in the tumor microenvironment to exert radiation-mediated tumor suppressionPriscilla S Simon, Kankana Bardhan, May R Chen, et al.Pageof 5