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Proceedings of the National Academy of Sciences of the United States of America|February 24, 2022
Abolishing the prelamin A ZMPSTE24 cleavage site leads to progeroid phenotypes with near-normal longevity in miceYuexia Wang, Khurts Shilagardi, Trunee Hsu, et al.Nature Medicine|November 9, 2019
Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cellsMunemasa Mori, Kazuhiro Furuhashi, Jennifer A Danielsson, et al.Science (New York, N.Y.)|October 29, 2011
BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activityReena Shakya, Latarsha J Reid, Colleen R Reczek, et al.Development (Cambridge, England)|January 25, 2002
Erythropoietin receptor signalling is required for normal brain developmentXiaobing Yu, John J Shacka, Jeffrey B Eells, et al.Ophthalmology|May 16, 2018
Clustered Regularly Interspaced Short Palindromic Repeats-Based Genome Surgery for the Treatment of Autosomal Dominant Retinitis PigmentosaYi-Ting Tsai, Wen-Hsuan Wu, Ting-Ting Lee, et al.Transplantation|February 19, 2010
Transplantation of reprogrammed embryonic stem cells improves visual function in a mouse model for retinitis pigmentosaNan-Kai Wang, Joaquin Tosi, Jennifer Mie Kasanuki, et al.Cell Reports. Medicine|March 22, 2024
CRISPR editing of anti-anemia drug target rescues independent preclinical models of retinitis pigmentosaNicholas D Nolan, Xuan Cui, Brian M Robbings, et al.Science Translational Medicine|September 10, 2025
Impaired TIM4-mediated efferocytosis by liver macrophages contributes to fibrosis in metabolic dysfunction-associated steatohepatitisHongxue Shi, Xiaobo Wang, Christopher Sloas, et al.Cell Metabolism|March 11, 2014
High-mobility group box 1 is dispensable for autophagy, mitochondrial quality control, and organ function in vivoPeter Huebener, Geum-Youn Gwak, Jean-Philippe Pradere, et al.Nature|February 5, 2025
RUNX2 promotes fibrosis via an alveolar-to-pathological fibroblast transitionYinshan Fang, Sanny S W Chung, Le Xu, et al.Pageof 9