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Nature Communications|February 3, 2026
Intradermal delivery of lipophilic siRNAs enables prolonged skin retention and sustained gene silencing in a porcine modelHassan H Fakih, Mohammad Zain Ui Abideen, Mohamad Omar Rachid, et al.Journal of Medicinal Chemistry|April 13, 2018
Rational Drug Design of Topically Administered Caspase 1 Inhibitors for the Treatment of Inflammatory AcneJean-François Fournier, Laurence Clary, Sandrine Chambon, et al.Bioorganic & Medicinal Chemistry|August 19, 2017
Discovery and process development of a novel TACE inhibitor for the topical treatment of psoriasisJean-Guy Boiteau, Gilles Ouvry, Jean-Marie Arlabosse, et al.Chemmedchem|January 13, 2018
Discovery and Characterization of CD12681, a Potent RORγ Inverse Agonist, Preclinical Candidate for the Topical Treatment of PsoriasisGilles Ouvry, Nicolas Atrux-Tallau, Franck Bihl, et al.Nature Communications|November 5, 2023
Rational design of a JAK1-selective siRNA inhibitor for the modulation of autoimmunity in the skinQi Tang, Hassan H Fakih, Mohammad Zain Ui Abideen, et al.Pageof 2