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Nutrients|April 18, 2015
The queuine micronutrient: charting a course from microbe to manClaire Fergus, Dominic Barnes, Mashael A Alqasem, et al.
Mucosal Immunology|April 12, 2026
Epithelial barrier DUOX2 serves as early immune defense in intestinal pathogen controlMaurice O'Mara, Suisheng Zhang, Claire Fergus, et al.
Chemical Communications (Cambridge, England)|March 10, 2020
The eukaryotic tRNA-guanine transglycosylase enzyme inserts queuine into tRNA via a sequential bi-bi mechanismMashael A Alqasem, Claire Fergus, J Mike Southern, et al.
Chemmedchem|June 23, 2023
Queuine Analogues Incorporating the 7-Aminomethyl-7-deazaguanine Core: Structure-Activity Relationships in the Treatment of Experimental Autoimmune EncephalomyelitisMichelle Cotter, Sreeja Varghese, Franciane Chevot, et al.
The Journal of Biological Chemistry|November 18, 2021
CRISPR/Cas9-mediated SARM1 knockout and epitope-tagged mice reveal that SARM1 does not regulate nuclear transcription, but is expressed in macrophagesCiara G Doran, Ryoichi Sugisawa, Michael Carty, et al.
Nutrients|March 28, 2020
Queuine Micronutrient Deficiency Promotes Warburg Metabolism and Reversal of the Mitochondrial ATP Synthase in Hela CellsPatti Hayes, Claire Fergus, Magda Ghanim, et al.
Nucleic Acids Research|February 17, 2017
In vivo modification of tRNA with an artificial nucleobase leads to full disease remission in an animal model of multiple sclerosisSreeja Varghese, Michelle Cotter, Franciane Chevot, et al.
Cells|March 29, 2023
Investigating the Impact of Delivery Routes for Exon Skipping Therapies in the CNS of DMD Mouse ModelsAmel Saoudi, Claire Fergus, Talia Gileadi, et al.
Nucleic Acids Research|May 19, 2021
The human tRNA-guanine transglycosylase displays promiscuous nucleobase preference but strict tRNA specificityClaire Fergus, Mashael Al-Qasem, Michelle Cotter, et al.
Molecular Therapy. Nucleic Acids|December 30, 2025
Behavioral improvement in dystrophic mdx23 mouse following repeated antisense oligonucleotides injectionsArtadokht Aghaeipour, Manuela Mitsogiannis, Claire Fergus, et al.
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