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Nano Letters|June 30, 2021
Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic DeviceSarah J Shepherd, Claude C Warzecha, Sagar Yadavali, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|February 20, 2021
Long-term stable reduction of low-density lipoprotein in nonhuman primates following in vivo genome editing of PCSK9Lili Wang, Camilo Breton, Claude C Warzecha, et al.Biomaterials Science|January 6, 2021
Helper lipid structure influences protein adsorption and delivery of lipid nanoparticles to spleen and liverRui Zhang, Rakan El-Mayta, Timothy J Murdoch, et al.Nature Communications|February 26, 2024
In situ combinatorial synthesis of degradable branched lipidoids for systemic delivery of mRNA therapeutics and gene editorsXuexiang Han, Junchao Xu, Ying Xu, et al.Molecular Therapy. Methods & Clinical Development|February 25, 2022
Prednisolone reduces the interferon response to AAV in cynomolgus macaques and may increase liver gene expressionLili Wang, Claude C Warzecha, Alexander Kistner, et al.Nature Biomedical Engineering|November 23, 2024
Optimization of the activity and biodegradability of ionizable lipids for mRNA delivery via directed chemical evolutionXuexiang Han, Mohamad-Gabriel Alameh, Ying Xu, et al.Nature Chemistry|July 9, 2024
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivoXuexiang Han, Mohamad-Gabriel Alameh, Ningqiang Gong, et al.Nature Nanotechnology|October 1, 2024
Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic deliveryLulu Xue, Gan Zhao, Ningqiang Gong, et al.Pageof 2