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Oncogenesis|June 18, 2022
The TIP60-ATM axis regulates replication fork stability in BRCA-deficient cellsEmily M Schleicher, Ashna Dhoonmoon, Lindsey M Jackson, et al.
Nature Communications|May 3, 2020
Ubiquitinated-PCNA protects replication forks from DNA2-mediated degradation by regulating Okazaki fragment maturation and chromatin assemblyTanay Thakar, Wendy Leung, Claudia M Nicolae, et al.
Nucleic Acids Research|December 6, 2021
Loss of MED12 activates the TGFβ pathway to promote chemoresistance and replication fork stability in BRCA-deficient cellsLindsey M Jackson, Ashna Dhoonmoon, Anastasia Hale, et al.
Cancer Research|February 26, 2013
PARI overexpression promotes genomic instability and pancreatic tumorigenesisKevin W O'Connor, Donniphat Dejsuphong, Eunmi Park, et al.
Plos Genetics|November 2, 2020
Dual genome-wide CRISPR knockout and CRISPR activation screens identify mechanisms that regulate the resistance to multiple ATR inhibitorsEmily M Schleicher, Ashna Dhoonmoon, Lindsey M Jackson, et al.
Oncogene|April 11, 2019
PARI (PARPBP) suppresses replication stress-induced myeloid differentiation in leukemia cellsClaudia M Nicolae, Michael J O'Connor, Emily M Schleicher, et al.
The Journal of Biological Chemistry|April 4, 2014
The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage toleranceClaudia M Nicolae, Erin R Aho, Alexander H S Vlahos, et al.
Nucleic Acids Research|March 11, 2015
A novel role for the mono-ADP-ribosyltransferase PARP14/ARTD8 in promoting homologous recombination and protecting against replication stressClaudia M Nicolae, Erin R Aho, Katherine N Choe, et al.
Cell Reports|February 27, 2025
Translesion-synthesis-mediated bypass of DNA lesions occurs predominantly behind replication forks restarted by PrimPolAshna Dhoonmoon, Julia R Ambrose, Sonal Garg, et al.
The Journal of Biological Chemistry|May 30, 2019
Error-prone replication of a 5-formylcytosine-mediated DNA-peptide cross-link in human cellsSpandana Naldiga, Shaofei Ji, Jenna Thomforde, et al.
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