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Xenobiotica; the Fate of Foreign Compounds in Biological Systems|August 25, 2022
A translational strategy employing physiologically based modelling to predict the pharmacological active dose of RO7119929, an oral prodrug of a targeted cancer immunotherapy TLR7 agonistCaroline Rynn, Kenichi Umehara, Tianyi Jiang, et al.
British Journal of Clinical Pharmacology|December 20, 2018
Population pharmacokinetics of oral ivermectin in venous plasma and dried blood spots in healthy volunteersUrs Duthaler, Claudia Suenderhauf, Mats O Karlsson, et al.
British Journal of Clinical Pharmacology|October 29, 2019
Pharmacokinetics and phenotyping properties of the Basel phenotyping cocktail combination capsule in healthy male adultsClaudia Suenderhauf, Benjamin Berger, Maxim Puchkov, et al.
Clinical Pharmacokinetics|May 15, 2022
Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel Phenotyping Cocktail DifferentlyUrs Duthaler, Fabio Bachmann, Claudia Suenderhauf, et al.
Pharmaceutical Research|July 30, 2013
In vitro and ex vivo investigation of the impact of luminal lipid phases on passive permeability of lipophilic small molecules using PAMPAConstantinos Markopoulos, Georgios Imanidis, Maria Vertzoni, et al.
CPT: Pharmacometrics & Systems Pharmacology|December 3, 2023
Evaluation of the potential impact on pharmacokinetics of various cytochrome P450 substrates of increasing IL-6 levels following administration of the T-cell bispecific engager glofitamabNassim Djebli, Neil Parrott, Felix Jaminion, et al.
International Journal of Pharmaceutics: X|March 19, 2025
Investigating the effect of whey and casein proteins on drug solubility from a paediatric drug absorption perspectiveMatthias Van der Veken, Joachim Brouwers, Neil Parrott, et al.
The AAPS Journal|June 20, 2019
Impact of Intracellular Concentrations on Metabolic Drug-Drug Interaction StudiesAndrea Treyer, Mohammed Ullah, Neil Parrott, et al.
The AAPS Journal|June 18, 2021
Use of Physiologically Based Pharmacokinetic Modeling for Predicting Drug-Food Interactions: Recommendations for Improving Predictive Performance of Low Confidence Food Effect ModelsChristian Wagner, Filippos Kesisoglou, Xavier J H Pepin, et al.
Clinical Pharmacokinetics|February 8, 2019
Physiologically Based Pharmacokinetic Modelling for First-In-Human Predictions: An Updated Model Building Strategy Illustrated with Challenging Industry Case StudiesNeil A Miller, Micaela B Reddy, Aki T Heikkinen, et al.
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