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Plos Genetics|September 26, 2022
Prostaglandins and calprotectin are genetically and functionally linked to the Inflammatory Bowel DiseasesMohamad Karaky, Gabrielle Boucher, Saraï Mola, et al.Human Molecular Genetics|June 3, 2017
Loss of hepatic LRPPRC alters mitochondrial bioenergetics, regulation of permeability transition and trans-membrane ROS diffusionAlexanne Cuillerier, Shamisa Honarmand, Virgilio J J Cadete, et al.Circulation. Cardiovascular Genetics|October 13, 2017
Characterization of a Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Model for the Study of Variant Pathogenicity: Validation of a <i>KCNJ2</i> MutationRoselle Gélinas, Nabil El Khoury, Marie-A Chaix, et al.Cell|August 11, 2022
Epigenetic reader SP140 loss of function drives Crohn's disease due to uncontrolled macrophage topoisomerasesHajera Amatullah, Isabella Fraschilla, Sreehaas Digumarthi, et al.Plos One|March 4, 2014
The dichotomous pattern of IL-12r and IL-23R expression elucidates the role of IL-12 and IL-23 in inflammationGaëlle Chognard, Lisa Bellemare, Adam-Nicolas Pelletier, et al.American Journal of Physiology. Regulatory, Integrative and Comparative Physiology|October 30, 2014
Specific targeting of the IL-23 receptor, using a novel small peptide noncompetitive antagonist, decreases the inflammatory responseChristiane Quiniou, Maria Domínguez-Punaro, Frank Cloutier, et al.Genome Medicine|November 11, 2021
Functional screen of inflammatory bowel disease genes reveals key epithelial functionsJessy Carol Ntunzwenimana, Gabrielle Boucher, Jean Paquette, et al.Plos Genetics|February 8, 2011
A meta-analysis of genome-wide association scans identifies IL18RAP, PTPN2, TAGAP, and PUS10 as shared risk loci for Crohn's disease and celiac diseaseEleonora A M Festen, Philippe Goyette, Todd Green, et al.Science Translational Medicine|September 27, 2019
<i>Lrrk2</i> alleles modulate inflammation during microbial infection of mice in a sex-dependent mannerBojan Shutinoski, Mansoureh Hakimi, Irene E Harmsen, et al.Nature Genetics|March 16, 2010
Genome-wide association identifies multiple ulcerative colitis susceptibility lociDermot P B McGovern, Agnès Gardet, Leif Törkvist, et al.Pageof 2