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Claus Ehrhardt

Showing results (11-20 of 17) with videos related to

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Bioorganic & Medicinal Chemistry Letters|March 11, 2015
trans-3,4-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part II: prime site exploration using an oxygen linkerHolger Sellner, Sylvain Cottens, Frédéric Cumin, et al.
Journal of Medicinal Chemistry|February 22, 2013
The discovery of novel potent trans-3,4-disubstituted pyrrolidine inhibitors of the human aspartic protease renin from in silico three-dimensional (3D) pharmacophore searchesEdwige Lorthiois, Werner Breitenstein, Frederic Cumin, et al.
Biochemical Pharmacology|March 15, 2023
Allosteric targeting resolves limitations of earlier LFA-1 directed modalitiesRiccardo V Mancuso, Gisbert Schneider, Marianne Hürzeler, et al.
Journal of Medicinal Chemistry|October 16, 2009
Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a potent and selective inhibitor of protein kinase C isotypesJürgen Wagner, Peter von Matt, Richard Sedrani, et al.
Bioorganic & Medicinal Chemistry Letters|October 26, 2005
Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitorsZheng Yin, Sejal J Patel, Wei-Ling Wang, et al.
Journal of Medicinal Chemistry|January 31, 2013
A novel class of oral direct renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophoreNils Ostermann, Simon Ruedisser, Claus Ehrhardt, et al.
ACS Chemical Biology|January 17, 2024
Targeting the Main Protease (M<sup>pro</sup>, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based MethodologiesNadide Altincekic, Nathalie Jores, Frank Löhr, et al.
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Showing results (11-20 of 17) with videos related to

Sort By:
Pageof 2
You have reached the last page of results.This site can display upto 17 results.
Bioorganic & Medicinal Chemistry Letters|March 11, 2015
trans-3,4-Disubstituted pyrrolidines as inhibitors of the human aspartyl protease renin. Part II: prime site exploration using an oxygen linkerHolger Sellner, Sylvain Cottens, Frédéric Cumin, et al.
Journal of Medicinal Chemistry|February 22, 2013
The discovery of novel potent trans-3,4-disubstituted pyrrolidine inhibitors of the human aspartic protease renin from in silico three-dimensional (3D) pharmacophore searchesEdwige Lorthiois, Werner Breitenstein, Frederic Cumin, et al.
Biochemical Pharmacology|March 15, 2023
Allosteric targeting resolves limitations of earlier LFA-1 directed modalitiesRiccardo V Mancuso, Gisbert Schneider, Marianne Hürzeler, et al.
Journal of Medicinal Chemistry|October 16, 2009
Discovery of 3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione (AEB071), a potent and selective inhibitor of protein kinase C isotypesJürgen Wagner, Peter von Matt, Richard Sedrani, et al.
Bioorganic & Medicinal Chemistry Letters|October 26, 2005
Peptide inhibitors of dengue virus NS3 protease. Part 2: SAR study of tetrapeptide aldehyde inhibitorsZheng Yin, Sejal J Patel, Wei-Ling Wang, et al.
Journal of Medicinal Chemistry|January 31, 2013
A novel class of oral direct renin inhibitors: highly potent 3,5-disubstituted piperidines bearing a tricyclic p3-p1 pharmacophoreNils Ostermann, Simon Ruedisser, Claus Ehrhardt, et al.
ACS Chemical Biology|January 17, 2024
Targeting the Main Protease (M<sup>pro</sup>, nsp5) by Growth of Fragment Scaffolds Exploiting Structure-Based MethodologiesNadide Altincekic, Nathalie Jores, Frank Löhr, et al.
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