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ACS Medicinal Chemistry Letters|June 6, 2014
Discovery of a Novel Series of CHK1 Kinase Inhibitors with a Distinctive Hinge Binding ModeXiaohua Huang, Cliff C Cheng, Thierry O Fischmann, et al.Bioorganic Chemistry|May 17, 2026
Discovery of 4-((2S,5R)-2-((difluoromethoxy)methyl)-5-(4-(trifluoromethyl)phenyl)piperidin-1-yl)-N-((R)-1-(4-(ethylsulfonyl)phenyl)-2-hydroxyethyl)benzamide as a potent, orally available RORγt inverse agonistWei Cao, Bing Liu, Ning Kang, et al.Journal of Medicinal Chemistry|April 11, 2025
Discovery of FLT3-ITD Inhibitor Clifutinib: A Novel Biphenylacetylene Urea Derivative in Clinical Trials for the Treatment of Relapsed/Refractory FLT3-ITD+ Acute Myeloid LeukemiaBing Liu, Ning Kang, Fang Yang, et al.Bioorganic & Medicinal Chemistry Letters|October 31, 2009
Discovery and optimization of antibacterial AccC inhibitorsCliff C Cheng, Gerald W Shipps, Zhiwei Yang, et al.Combinatorial Chemistry & High Throughput Screening|June 18, 2009
Inhibitors of the lipid phosphatase SHIP2 discovered by high-throughput affinity selection-mass spectrometry screening of combinatorial librariesD Allen Annis, Cliff C Cheng, Cheng-Chi Chuang, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Pyridine Carboxamides: Potent Palm Site Inhibitors of HCV NS5B PolymeraseCliff C Cheng, Xiaohua Huang, Gerald W Shipps, et al.Bioorganic & Medicinal Chemistry Letters|March 12, 2010
Inhibitors of hepatitis C virus polymerase: synthesis and characterization of novel 2-oxy-6-fluoro-N-((S)-1-hydroxy-3-phenylpropan-2-yl)-benzamidesCliff C Cheng, Gerald W Shipps, Zhiwei Yang, et al.Combinatorial Chemistry & High Throughput Screening|June 2, 2012
Application of affinity selection-mass spectrometry assays to purification and affinity-based screening of the chemokine receptor CXCR4Charles E Whitehurst, Zhiping Yao, Denise Murphy, et al.ACS Medicinal Chemistry Letters|June 6, 2014
Discovery and Hit-to-Lead Optimization of Non-ATP Competitive MK2 (MAPKAPK2) InhibitorsXiaohua Huang, Gerald W Shipps, Cliff C Cheng, et al.Journal of Biomolecular Screening|February 24, 2006
Discovery and characterization of orthosteric and allosteric muscarinic M2 acetylcholine receptor ligands by affinity selection-mass spectrometryCharles E Whitehurst, Naim Nazef, D Allen Annis, et al.Pageof 2