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Proceedings of the National Academy of Sciences of the United States of America|November 17, 2009
Markedly enhanced colon tumorigenesis in Apc(Min) mice lacking glutathione S-transferase PiKenneth J Ritchie, Shaun Walsh, Owen J Sansom, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|May 28, 2014
Phenobarbital-mediated tumor promotion in transgenic mice with humanized CAR and PXRAlbert Braeuning, Alina Gavrilov, Susan Brown, et al.
The Journal of Pharmacology and Experimental Therapeutics|April 17, 2007
Conditional deletion of cytochrome P450 oxidoreductase in the liver and gastrointestinal tract: a new model for studying the functions of the P450 systemRobert D Finn, Aileen W McLaren, Dianne Carrie, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 9, 2017
Novel Pathways of Ponatinib Disposition Catalyzed By CYP1A1 Involving Generation of Potentially Toxic MetabolitesDe Lin, Rumen Kostov, Jeffrey T-J Huang, et al.
Molecular Pharmacology|February 7, 2015
Cytochrome b5 is a major determinant of human cytochrome P450 CYP2D6 and CYP3A4 activity in vivoColin J Henderson, Lesley A McLaughlin, Nico Scheer, et al.
Molecular Pharmacology|May 1, 2010
Deletion of microsomal cytochrome b5 profoundly affects hepatic and extrahepatic drug metabolismLesley A McLaughlin, Sebastien Ronseaux, Robert D Finn, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|February 19, 2015
Evidence that the capacity of nongenotoxic carcinogens to induce oxidative stress is subject to marked variabilityColin J Henderson, Amy R Cameron, Lynsey Chatham, et al.
Transgenic Research|August 3, 2010
Cytochrome b5 null mouse: a new model for studying inherited skin disorders and the role of unsaturated fatty acids in normal homeostasisRobert D Finn, Lesley A McLaughlin, Catherine Hughes, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 12, 2013
A role for cytochrome b5 in the In vivo disposition of anticancer and cytochrome P450 probe drugs in miceColin J Henderson, Lesley A McLaughlin, Robert D Finn, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|March 28, 2014
Deletion of 30 murine cytochrome p450 genes results in viable mice with compromised drug metabolismNico Scheer, Lesley A McLaughlin, Anja Rode, et al.
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