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Proteomics|February 26, 2003
Protein expression profiling of glutathione S-transferase pi null mice as a strategy to identify potential markers of resistance to paracetamol-induced toxicity in the liverNeil R Kitteringham, Helen Powell, Rosalind E Jenkins, et al.
Nature|February 2, 2017
Feedback control of AHR signalling regulates intestinal immunityChris Schiering, Emma Wincent, Amina Metidji, et al.
The Journal of Pharmacology and Experimental Therapeutics|March 1, 2025
Use of an extensively humanized mouse model to predict the risk of drug-drug interactions in patients receiving dexamethasoneJacob George, James D Chalmers, Kevin-Sebastien Coquelin, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 20, 2013
Pyrethroid activity-based probes for profiling cytochrome P450 activities associated with insecticide interactionsHanafy M Ismail, Paul M O'Neill, David W Hong, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 24, 2011
Effect of hepatic cytochrome P450 (P450) oxidoreductase deficiency on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-DNA adduct formation in P450 reductase conditional null miceVolker M Arlt, Rajinder Singh, Marie Stiborová, et al.
Toxicology|February 18, 2014
Cytochrome b5 and epoxide hydrolase contribute to benzo[a]pyrene-DNA adduct formation catalyzed by cytochrome P450 1A1 under low NADPH:P450 oxidoreductase conditionsMarie Stiborová, Michaela Moserová, Věra Černá, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 19, 2025
Application of a mouse model humanized for cytochrome P450-mediated drug metabolism to predict drug-drug interactions between a peptide and small molecule drugsYury Kapelyukh, Charlotte Gabel-Jensen, Alastaire Kenneth MacLeod, et al.
Archives of Toxicology|January 26, 2018
Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) miceLindsay Reed, Iveta Mrizova, Frantisek Barta, et al.
Cancer Research|April 5, 2005
Environmental pollutant and potent mutagen 3-nitrobenzanthrone forms DNA adducts after reduction by NAD(P)H:quinone oxidoreductase and conjugation by acetyltransferases and sulfotransferases in human hepatic cytosolsVolker M Arlt, Marie Stiborova, Colin J Henderson, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|March 3, 2011
Role of cytochromes P450 1A1/2 in detoxication and activation of carcinogenic aristolochic acid I: studies with the hepatic NADPH:cytochrome P450 reductase null (HRN) mouse modelKaterina Levová, Michaela Moserová, Vera Kotrbová, et al.
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