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Archives of Toxicology|May 30, 2019
Uptake and effects of orally ingested polystyrene microplastic particles in vitro and in vivoValerie Stock, Linda Böhmert, Elisa Lisicki, et al.
Carcinogenesis|January 22, 2008
Metabolic activation of benzo[a]pyrene in vitro by hepatic cytochrome P450 contrasts with detoxification in vivo: experiments with hepatic cytochrome P450 reductase null miceVolker M Arlt, Marie Stiborová, Colin J Henderson, et al.
The Biochemical Journal|May 7, 2002
Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4 genes in the livers of male and female miceSimon A Chanas, Qing Jiang, Michael McMahon, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|October 23, 2012
NADPH-cytochrome P450 oxidoreductase: roles in physiology, pharmacology, and toxicologyDavid S Riddick, Xinxin Ding, C Roland Wolf, et al.
Plos One|October 25, 2011
Humanizing π-class glutathione S-transferase regulation in a mouse model alters liver toxicity in response to acetaminophen overdoseMatthew P Vaughn, Debika Biswal Shinohara, Nicole Castagna, et al.
Proceedings of the National Academy of Sciences of the United States of America|February 5, 2024
Acceleration of infectious disease drug discovery and development using a humanized model of drug metabolismA Kenneth MacLeod, Kevin-Sebastien Coquelin, Leticia Huertas, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 7, 2016
The Role of Protein-Protein and Protein-Membrane Interactions on P450 FunctionEmily E Scott, C Roland Wolf, Michal Otyepka, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|May 26, 2017
Xenobiotic CAR Activators Induce Dlk1-Dio3 Locus Noncoding RNA Expression in Mouse LiverLucie Pouché, Antonio Vitobello, Michael Römer, et al.
JCI Insight|July 1, 2016
Attenuation of lung fibrosis in mice with a clinically relevant inhibitor of glutathione-S-transferase πDavid H McMillan, Jos Lj van der Velden, Karolyn G Lahue, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|April 3, 2014
Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptorsRaphaëlle Luisier, Harri Lempiäinen, Nina Scherbichler, et al.
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