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Biophysical Chemistry|May 30, 2013
Thiazotropsin aggregation and its relationship to molecular recognition in the DNA minor grooveMarie-Virginie Salvia, Fiona Addison, Hasan Y Alniss, et al.Journal of Autoimmunity|May 16, 2015
Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasomeJustyna Rzepecka, Miguel A Pineda, Lamyaa Al-Riyami, et al.Journal of Medicinal Chemistry|January 11, 2020
Mycobacterium tuberculosis Decaprenylphosphoryl-β-d-ribose Oxidase Inhibitors: Expeditious Reconstruction of Suboptimal Hits into a Series with Potent in Vivo ActivityJennifer A Borthwick, Carlos Alemparte, Ian Wall, et al.The Journal of Antimicrobial Chemotherapy|January 27, 2022
Intranasally administered S-MGB-364 displays antitubercular activity and modulates the host immune response to Mycobacterium tuberculosis infectionNathan S Kieswetter, Mumin Ozturk, Lerato Hlaka, et al.Journal of Medicinal Chemistry|October 27, 2007
Antimicrobial lexitropsins containing amide, amidine, and alkene linking groupsNahoum G Anthony, David Breen, Joanna Clarke, et al.Molecules (Basel, Switzerland)|October 20, 2018
Failure of the Anti-Inflammatory Parasitic Worm Product ES-62 to Provide Protection in Mouse Models of Type I Diabetes, Multiple Sclerosis, and Inflammatory Bowel DiseaseJames Doonan, David Thomas, Michelle H Wong, et al.European Journal of Medicinal Chemistry|May 26, 2017
An evaluation of Minor Groove Binders as anti-fungal and anti-mycobacterial therapeuticsFraser J Scott, Ryan J O Nichol, Abedawn I Khalaf, et al.ACS Infectious Diseases|November 29, 2022
Insights into the Spectrum of Activity and Mechanism of Action of MGB-BP-3Charlotte Hind, Melanie Clifford, Charlotte Woolley, et al.Bioorganic & Medicinal Chemistry Letters|February 24, 2007
M4 agonists/5HT7 antagonists with potential as antischizophrenic drugs: serominic compoundsColin J Suckling, John A Murphy, Abedawn I Khalaf, et al.Journal of Medicinal Chemistry|December 22, 2016
Discovery of a Potent, Cell Penetrant, and Selective p300/CBP-Associated Factor (PCAF)/General Control Nonderepressible 5 (GCN5) Bromodomain Chemical ProbePhilip G Humphreys, Paul Bamborough, Chun-Wa Chung, et al.Pageof 8