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Nature Communications|June 9, 2021
Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesisJoshua D G Leach, Nikola Vlahov, Petros Tsantoulis, et al.
Science Translational Medicine|August 17, 2018
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescenceThomas G Bird, Miryam Müller, Luke Boulter, et al.
Nature|June 3, 2021
NOTUM from Apc-mutant cells biases clonal competition to initiate cancerDustin J Flanagan, Nalle Pentinmikko, Kalle Luopajärvi, et al.
EMBO Molecular Medicine|January 11, 2022
THEM6-mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancerArnaud Blomme, Coralie Peter, Ernest Mui, et al.
Nature Cell Biology|November 13, 2024
Hepatocellular senescence induces multi-organ senescence and dysfunction via TGFβChristos Kiourtis, Maria Terradas-Terradas, Lucy M Gee, et al.
Journal of Experimental & Clinical Cancer Research : CR|February 29, 2024
JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumorsKathryn A F Pennel, Phimmada Hatthakarnkul, Colin S Wood, et al.
Nature Communications|December 8, 2022
Epithelial TGFβ engages growth-factor signalling to circumvent apoptosis and drive intestinal tumourigenesis with aggressive featuresDustin J Flanagan, Raheleh Amirkhah, David F Vincent, et al.
Nature Metabolism|November 10, 2020
c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosisJack Leslie, Marina García Macia, Saimir Luli, et al.
Nature Genetics|January 8, 2021
The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancerArafath K Najumudeen, Fatih Ceteci, Sigrid K Fey, et al.
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