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Molecular Therapy : the Journal of the American Society of Gene Therapy|May 7, 2025
Locking CBL TKBD in its native conformation presents a novel therapeutic opportunity in mutant CBL-dependent leukemiaSyed Feroj Ahmed, Jayanthi Anand, Wei Zhang, et al.
The Journal of Investigative Dermatology|March 28, 2015
Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt SignalingJeffrey S Pawlikowski, Claire Brock, Sheau-Chiann Chen, et al.
Proceedings of the National Academy of Sciences of the United States of America|June 23, 2022
Glycan degradation promotes macroautophagyAlice D Baudot, Victoria M-Y Wang, Josh D Leach, et al.
The Journal of Pathology. Clinical Research|July 25, 2022
CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancerKathryn Af Pennel, Jean A Quinn, Colin Nixon, et al.
Molecular Cell|September 8, 2019
mTORC1 Activation Requires DRAM-1 by Facilitating Lysosomal Amino Acid EffluxFlorian Beaumatin, Jim O'Prey, Valentin J A Barthet, et al.
Cell Death and Differentiation|June 17, 2017
TGFβ pathway limits dedifferentiation following WNT and MAPK pathway activation to suppress intestinal tumourigenesisPatrizia Cammareri, David F Vincent, Michael C Hodder, et al.
The Journal of Cell Biology|October 24, 2012
N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopodsXinzi Yu, Tobias Zech, Laura McDonald, et al.
Disease Models & Mechanisms|April 17, 2025
A precision image-guided model of stereotactic ablative radiotherapy for hepatocellular carcinomaStephanie May, Katrina Stevenson, Bashaer Alqarafi, et al.
Developmental Cell|December 27, 2011
Rab25 and CLIC3 collaborate to promote integrin recycling from late endosomes/lysosomes and drive cancer progressionMarta A Dozynkiewicz, Nigel B Jamieson, Iain Macpherson, et al.
Cancer Research|October 16, 2024
KRAS Loss of Heterozygosity Promotes MAPK-Dependent Pancreatic Ductal Adenocarcinoma Initiation and Induces Therapeutic Sensitivity to MEK InhibitionSigrid K Fey, Arafath K Najumudeen, Dale M Watt, et al.
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