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Neurobiology of Aging|October 17, 2017
Atypical PKC, PKCλ/ι, activates β-secretase and increases Aβ<sub>1-40/42</sub> and phospho-tau in mouse brain and isolated neuronal cells, and may link hyperinsulinemia and other aPKC activators to development of pathological and memory abnormalities in Alzheimer's diseaseMini P Sajan, Barbara C Hansen, Margaret G Higgs, et al.Pageof 3