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Bioorganic & Medicinal Chemistry Letters|December 18, 2007
N-(3-(phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: structure, synthesis and SARHolly L Deak, John R Newcomb, Joseph J Nunes, et al.Bioorganic & Medicinal Chemistry Letters|February 6, 2007
Discovery of novel 2,3-diarylfuro[2,3-b]pyridin-4-amines as potent and selective inhibitors of Lck: synthesis, SAR, and pharmacokinetic propertiesMatthew W Martin, John Newcomb, Joseph J Nunes, et al.Bioorganic & Medicinal Chemistry Letters|February 7, 2007
Discovery of 4-amino-5,6-biaryl-furo[2,3-d]pyrimidines as inhibitors of Lck: development of an expedient and divergent synthetic route and preliminary SARErin F DiMauro, John Newcomb, Joseph J Nunes, et al.Journal of Medicinal Chemistry|June 30, 2015
Discovery of Highly Isoform Selective Thiazolopiperidine Inhibitors of Phosphoinositide 3-Kinase γPhilip N Collier, David Messersmith, Arnaud Le Tiran, et al.Journal of Medicinal Chemistry|February 19, 2008
Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activityMatthew W Martin, John Newcomb, Joseph J Nunes, et al.Journal of Medicinal Chemistry|December 6, 2021
Discovery of Novel, Orally Bioavailable Pyrimidine Ether-Based Inhibitors of ELOVL1Michael J Boyd, Philip N Collier, Michael P Clark, et al.Journal of Medicinal Chemistry|March 7, 2008
Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activationErin F DiMauro, John Newcomb, Joseph J Nunes, et al.Journal of Medicinal Chemistry|November 8, 2021
Discovery and Optimization of Pyrazole Amides as Inhibitors of ELOVL1Jon H Come, Timothy J Senter, Michael P Clark, et al.Journal of Medicinal Chemistry|August 4, 2006
Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis, SAR, and in vivo antiinflammatory activityMatthew W Martin, John Newcomb, Joseph J Nunes, et al.Journal of Medicinal Chemistry|September 15, 2006
Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activityErin F DiMauro, John Newcomb, Joseph J Nunes, et al.Pageof 12