Showing results (1-10 of 37) with videos related to
Sort By:
Pageof 4
Current Opinion in Drug Discovery & Development|January 5, 2008
Modeling of drug-transporter interactions using structural informationSusanne Winiwarter, Constanze HilgendorfMolecular Pharmaceutics|March 23, 2017
In Vitro Intrinsic Permeability: A Transporter-Independent Measure of Caco-2 Cell Permeability in Drug Design and DevelopmentLinda Fredlund, Susanne Winiwarter, Constanze HilgendorfMolecular Pharmaceutics|October 10, 2013
Resolving the distribution-metabolism interplay of eight OATP substrates in the standard clearance assay with suspended human cryopreserved hepatocytesPär Nordell, Susanne Winiwarter, Constanze HilgendorfInternational Journal of Pharmaceutics|April 14, 2016
Excised segments of rat small intestine in Ussing chamber studies: A comparison of native and stripped tissue viability and permeability to drugsErik Sjögren, Johanna Eriksson, Charlotta Vedin, et al.Journal of Pharmaceutical Sciences|April 16, 2020
Industrial Approach to Determine the Relative Contribution of Seven Major UGT Isoforms to Hepatic GlucuronidationDavid Busse, Sara Leandersson, Sara Amberntsson, et al.European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences|May 18, 2006
Variability in mRNA expression of ABC- and SLC-transporters in human intestinal cells: comparison between human segments and Caco-2 cellsAnnick Seithel, Johan Karlsson, Constanze Hilgendorf, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|August 7, 2013
Utility of in vitro systems and preclinical data for the prediction of human intestinal first-pass metabolism during drug discovery and preclinical developmentFredrik H Karlsson, Salim Bouchene, Constanze Hilgendorf, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 15, 2007
Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell linesConstanze Hilgendorf, Gustav Ahlin, Annick Seithel, et al.Molecular Pharmaceutics|April 5, 2005
Selective downregulation of the MDR1 gene product in Caco-2 cells by stable transfection to prove its relevance in secretory drug transportConstanze Hilgendorf, Hilde Spahn-Langguth, Magdalena Rhedin, et al.Drug Metabolism and Disposition: the Biological Fate of Chemicals|September 11, 2009
Endogenous gene and protein expression of drug-transporting proteins in cell lines routinely used in drug discovery programsGustav Ahlin, Constanze Hilgendorf, Johan Karlsson, et al.Pageof 4