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Biomolecules|November 27, 2025
The Identification of a Sub-Micromolar Peptide-Based Protein Arginine Methyltransferase 1 (PRMT1) Inhibitor from a Plate-Based Screening AssayTina M Sawatzky, Sarah A Mann, Jordan Shauna Tucker, et al.
Journal of Extracellular Vesicles|June 23, 2015
A novel role for peptidylarginine deiminases in microvesicle release reveals therapeutic potential of PAD inhibition in sensitizing prostate cancer cells to chemotherapySharad Kholia, Samireh Jorfi, Paul R Thompson, et al.
The Journal of Pharmacology and Experimental Therapeutics|January 31, 2015
Inhibiting protein arginine deiminases has antioxidant consequencesErin E Witalison, Xiangli Cui, Anne B Hofseth, et al.
Biochemistry|May 18, 2010
Substrate specificity and kinetic studies of PADs 1, 3, and 4 identify potent and selective inhibitors of protein arginine deiminase 3Bryan Knuckley, Corey P Causey, Justin E Jones, et al.
ACS Chemical Biology|October 19, 2011
Synthesis and screening of a haloacetamidine containing library to identify PAD4 selective inhibitorsJustin E Jones, Jessica L Slack, Pengfei Fang, et al.
Chemical Communications (Cambridge, England)|August 27, 2010
A fluopol-ABPP HTS assay to identify PAD inhibitorsBryan Knuckley, Justin E Jones, Daniel A Bachovchin, et al.
Developmental Biology|May 5, 2011
Protein deiminases: new players in the developmentally regulated loss of neural regenerative abilitySigrun Lange, Stefanie Gögel, Kit-Yi Leung, et al.
Plos Genetics|June 10, 2011
Genome-wide analysis reveals PADI4 cooperates with Elk-1 to activate c-Fos expression in breast cancer cellsXuesen Zhang, Matthew J Gamble, Sonja Stadler, et al.
American Journal of Physiology. Gastrointestinal and Liver Physiology|March 19, 2011
Suppression of colitis in mice by Cl-amidine: a novel peptidylarginine deiminase inhibitorAlexander A Chumanevich, Corey P Causey, Bryan A Knuckley, et al.
Journal of Medicinal Chemistry|September 3, 2011
The development of N-α-(2-carboxyl)benzoyl-N(5)-(2-fluoro-1-iminoethyl)-l-ornithine amide (o-F-amidine) and N-α-(2-carboxyl)benzoyl-N(5)-(2-chloro-1-iminoethyl)-l-ornithine amide (o-Cl-amidine) as second generation protein arginine deiminase (PAD) inhibitorsCorey P Causey, Justin E Jones, Jessica L Slack, et al.
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