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ACS Chemical Neuroscience|January 7, 2015
Identification and characterization of ML352: a novel, noncompetitive inhibitor of the presynaptic choline transporterElizabeth A Ennis, Jane Wright, Cassandra L Retzlaff, et al.Bioorganic & Medicinal Chemistry Letters|May 10, 2006
Development of N-4,6-pyrimidine-N-alkyl-N'-phenyl ureas as orally active inhibitors of lymphocyte specific tyrosine kinaseJennifer A Maier, Todd A Brugel, Mark Sabat, et al.Bioorganic & Medicinal Chemistry Letters|August 23, 2012
Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activatorMargrith E Mattmann, Haibo Yu, Zhihong Lin, et al.ACS Chemical Neuroscience|May 18, 2016
ML418: The First Selective, Sub-Micromolar Pore Blocker of Kir7.1 Potassium ChannelsDaniel R Swale, Haruto Kurata, Sujay V Kharade, et al.The Journal of Clinical Investigation|November 16, 2013
Inhibition of the TRPC5 ion channel protects the kidney filterThomas Schaldecker, Sookyung Kim, Constantine Tarabanis, et al.ACS Chemical Neuroscience|November 27, 2018
Analgesic Effects of the GIRK Activator, VU0466551, Alone and in Combination with Morphine in Acute and Persistent Pain ModelsKristopher K Abney, Michael Bubser, Yu Du, et al.ACS Chemical Biology|May 28, 2011
Selective inhibition of the K(ir)2 family of inward rectifier potassium channels by a small molecule probe: the discovery, SAR, and pharmacological characterization of ML133Hao-Ran Wang, Meng Wu, Haibo Yu, et al.Bioorganic & Medicinal Chemistry Letters|August 22, 2006
Design and synthesis of novel N-sulfonyl-2-indole carboxamides as potent PPAR-gamma binding agents with potential application to the treatment of osteoporosisCorey R Hopkins, Steven V O'neil, Michael C Laufersweiler, et al.Scientific Reports|November 17, 2016
An insecticide resistance-breaking mosquitocide targeting inward rectifier potassium channels in vectors of Zika virus and malariaDaniel R Swale, Darren W Engers, Sean R Bollinger, et al.ACS Infectious Diseases|March 6, 2019
Discovery and Characterization of 2-Nitro-5-(4-(phenylsulfonyl)piperazin-1-yl)- N-(pyridin-4-ylmethyl)anilines as Novel Inhibitors of the Aedes aegypti Kir1 ( AeKir1) ChannelChristopher D Aretz, M Jane Morwitzer, Austin G Sanford, et al.Pageof 13